NCBI Accession #
NP_194339.1
NCBI GenBank Nucleotide #
NM_118742.2
NCBI Official Full Name
NB-ARC domain-containing disease resistance protein
NCBI Official Symbol
RPS2
NCBI Official Synonym Symbols
DISEASE RESISTANCE PROTEIN RPS2; F20B18.200; F20B18_200; RESISTANT TO P. SYRINGAE 2
NCBI Protein Information
NB-ARC domain-containing disease resistance protein
NCBI Summary
Encodes a plasma membrane protein with leucine-rich repeat, leucine zipper, and P loop domains that confers resistance to Pseudomonas syringae infection by interacting with the avirulence gene avrRpt2. RPS2 protein interacts directly with plasma membrane associated protein RIN4 and this interaction is disrupted by avrRpt2.
UniProt Protein Name
Disease resistance protein RPS2
UniProt Synonym Protein Names
Resistance to Pseudomonas syringae protein 2
UniProt Primary Accession #
Q42484
UniProt Secondary Accession #
O82096; Q8L3R0; Q8L3W3; Q8L4X9; Q8L4Y0; Q8L587; Q8L5B3; Q8LKZ8; Q8LKZ9; Q8LL00; Q8LL01
UniProt Related Accession #
Q42484
UniProt Comments
Disease resistance (R) protein that specifically recognizes the AvrRpt2 type III effector avirulence protein from Pseudomonas syringae. Resistance proteins guard the plant against pathogens that contain an appropriate avirulence protein via an indirect interaction with this avirulence protein. That triggers a defense system including the hypersensitive response, which restricts the pathogen growth. Acts via its interaction with RIN4, and probably triggers the plant resistance when RIN4 is degraded by AvrRpt2.