NCBI Accession #
NP_174620.2
NCBI GenBank Nucleotide #
NM_103079.4
NCBI Official Full Name
Disease resistance protein (CC-NBS-LRR class) family
NCBI Official Symbol
ADR1
NCBI Official Synonym Symbols
ACTIVATED DISEASE RESISTANCE 1; F10C21.19
NCBI Protein Information
Disease resistance protein (CC-NBS-LRR class) family
NCBI Summary
Encodes a NBS-LRR disease resistance protein that possesses N-terminal kinase subdomains. Activation tagged mutant of ADR1 showed elevated levels of SA and reactive oxygen species in addition to number of defense gene transcripts. Exhibits resistance to number of microbial pathogens.
UniProt Protein Name
Disease resistance protein ADR1
UniProt Synonym Protein Names
Activated disease resistance protein 1
UniProt Primary Accession #
Q9FW44
UniProt Related Accession #
Q9FW44
UniProt Comments
Disease resistance (R) protein that mediates resistance against Hyaloperonospora parasitica in a salicylic acid-dependent manner. Also mediates resistance against Erysiphe cichoracearum is both salicylic acid-dependent and partially NPR1-dependent. Resistance proteins guard the plant against pathogens that contain an appropriate avirulence protein via an indirect interaction with this avirulence protein. That triggers a defense system including the hypersensitive response, which restricts the pathogen growth.