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Delta-1-pyrroline-5-carboxylate dehydrogenase 12A1, mitochondrial (ALDH12A1), Recombinant Protein
Cat: RP08825
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:
Product Info
Full Product Name
Recombinant Arabidopsis thaliana Delta-1-pyrroline-5-carboxylate dehydrogenase 12A1, mitochondrial (ALDH12A1) , partial
Product Gene Name
ALDH12A1 recombinant protein
Product Synonym Gene Name
ALDH12A1
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
61,773 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
Delta-1-pyrroline-5-carboxylate dehydrogenase
NCBI/Uniprot Data
NCBI Accession #
NP_568955.1
NCBI GI #
18424599
NCBI GenBank Nucleotide #
NM_125647.4
NCBI GeneID
836373
NCBI Official Full Name
aldehyde dehydrogenase 12A1
NCBI Official Symbol
ALDH12A1
NCBI Official Synonym Symbols
aldehyde dehydrogenase 12A1; ARABIDOPSIS THALIANA DELTA1-PYRROLINE-5-CARBOXYLATE DEHYDROGENASE; ATP5CDH; DELTA1-PYROLINE-5-CARBOXYLATE DEHYDROGENASE; DELTA1-PYRROLINE-5-CARBOXYLATE DEHYDROGENASE; K19B1.14; K19B1_14; P5CDH
NCBI Protein Information
aldehyde dehydrogenase 12A1
NCBI Summary
Encodes mitochondrial Delta-pyrroline-5- carboxylate dehydrogenase. Involved in the catabolism of proline to glutamate. Involved in protection from proline toxicity. Induced at pathogen infection sites. P5CDH and SRO5 (an overlapping gene in the sense orientation) generate 24-nt and 21-nt siRNAs, which together are components of a regulatory loop controlling reactive oxygen species (ROS) production and stress response.
UniProt Gene Name
ALDH12A1
UniProt Synonym Gene Names
P5CDH; AtP5CDH; P5C dehydrogenase
UniProt Protein Name
Delta-1-pyrroline-5-carboxylate dehydrogenase 12A1, mitochondrial
UniProt Synonym Protein Names
Aldehyde dehydrogenase family 12 member A1; L-glutamate gamma-semialdehyde dehydrogenase
UniProt Primary Accession #
Q8VZC3
UniProt Secondary Accession #
Q93Y55; Q9FJJ2
UniProt Related Accession #
Q8VZC3
UniProt Comments
Plays a role in the inhibition of programmed cell death by converting the toxic proline catabolism intermediate (s)-1-pyrroline-5-carboxylate (P5C) to glutamate.
For research use only, not for clinical use.