Datura Stramonium Lectin (DSL), Unconjugated

Carbohydrate-binding site recognition (beta-1,4) -linked N-acetylglucosamine oligomers favored chitosan or chitosaccharides over individual n-acetylglucosamine residues. The lectin binds well in the acidic pH range, but its affinity decreases above pH 8.0. DSL also binds well to N-acetyllactamine and oligomers containing repeated n-acetyllactamine sequences. A branched-chain pentasaccharide consisting of two n-acetyllactodicosse-linked mannose (beta-1,6) and (beta-1,2) has been reported to be the most potent agglutination inhibitor.