NCBI Accession #
NP_177549.1
NCBI GenBank Nucleotide #
NM_106069.3
NCBI Official Full Name
desulfo-glucosinolate sulfotransferase 18
NCBI Official Symbol
SOT18
NCBI Official Synonym Symbols
ARABIDOPSIS SULFOTRANSFERASE 5B; ATSOT18; ATST5B; desulfo-glucosinolate sulfotransferase 18; DESULFO-GLUCOSINOLATE SULFOTRANSFERASE 18; F2P9.4; F2P9_4
NCBI Protein Information
desulfo-glucosinolate sulfotransferase 18
NCBI Summary
encodes a desulfoglucosinolate sulfotransferase, involved in the final step of glucosinolate core structure biosynthesis. Has a broad-substrate specificity with preference with methionine-derived desulfoglucosinolates.
UniProt Synonym Gene Names
ST5B; AtSOT18; AtST5b
UniProt Protein Name
Cytosolic sulfotransferase 18
UniProt Synonym Protein Names
Desulfo-glucosinolate sulfotransferase B; Sulfotransferase 5B; AtST5b
UniProt Primary Accession #
Q9C9C9
UniProt Secondary Accession #
Q8LA18
UniProt Related Accession #
Q9C9C9
UniProt Comments
Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of desulfo-glucosinolates (dsGSs), the final step in the biosynthesis of the glucosinolate core structure. Preferred substrate are the long-chain desulfo-glucosinolates, 7-methylthioheptyl and 8-methylthiooctyl, derived from methionine. Substrate preference is desulfo-benzyl glucosinolate > desulfo-4-methylthiobutyl glucosinolate > desulfo-6-methylthiohexyl glucosinolate > desulfo-3-methylthiopropyl glucosinolate > desulfo-indol-3-yl methyl glucosinolate > desulfo-singrin > desulfo-3-butenyl glucosinolate.