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Cytochrome P450 98A3 (CYP98A3), Recombinant Protein
Cat: RP07981
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:
Product Info
Full Product Name
Recombinant Arabidopsis thaliana Cytochrome P450 98A3 (CYP98A3) , partial
Product Gene Name
CYP98A3 recombinant protein
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
57,927 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
Cytochrome
NCBI/Uniprot Data
NCBI Accession #
NP_850337.1
NCBI GI #
30688445
NCBI GenBank Nucleotide #
NM_180006.2
NCBI GeneID
818686
NCBI Official Full Name
cytochrome P450, family 98, subfamily A, polypeptide 3
NCBI Official Symbol
CYP98A3
NCBI Official Synonym Symbols
cytochrome P450; family 98; polypeptide 3; REDUCED EPIDERMAL FLUORESCENCE 8; REF8; subfamily A; T20B5.9; T20B5_9
NCBI Protein Information
cytochrome P450, family 98, subfamily A, polypeptide 3
NCBI Summary
encodes coumarate 3-hydroxylase (C3H), a P450-dependent monooxygenase. Involved in lignin biosynthesis and flavonoid biosynthesis. Also affects the biosynthesis of coumarins such as scopoletin and scopolin as a branching-out-pathway from the phenylpropanoid acid level.
UniProt Gene Name
CYP98A3
UniProt Synonym Gene Names
C3'H; REF8; C3'H
UniProt Protein Name
Cytochrome P450 98A3
UniProt Synonym Protein Names
Protein REDUCED EPIDERMAL FLUORESCENCE 8; p-coumaroylshikimate/quinate 3'-hydrolxylase; C3'H
UniProt Primary Accession #
O22203
UniProt Secondary Accession #
Q0WWH4; Q940C7
UniProt Related Accession #
O22203
UniProt Comments
Cytochrome P450 which catalyzes 3'-hydroxylation of p-coumaric esters of shikimic/quinic acids to form lignin monomers. Can use p-coumarate, p-coumaraldehyde, p-coumaroyl methyl ester, 5-O-(4-coumaroyl) D-quinate and 5-O-(4-coumaroyl) shikimate as substrates, but not p-coumaryl alcohol, p-coumaroyl CoA, 1-O-p-coumaroyl-beta-D-glucose, p-hydroxy-cinnamyl alcohol, cinnamate, caffeate or ferulate. Has a weak activity on tri(p-coumaroyl)spermidine, but none on triferuloylspermidine. Hydroxylates preferentially the 5-O-isomer, but can also convert the 4-O- and 3-O-isomers with a lower efficiency. Involved in the biosynthesis of the coumarins scopoletin and scopolin. Essential for the biosynthesis of lignin.
For research use only, not for clinical use.