NCBI Accession #
NP_194878.1
NCBI GenBank Nucleotide #
NM_119299.3
NCBI Official Full Name
cytochrome P450, family 83, subfamily B, polypeptide 1
NCBI Official Symbol
CYP83B1
NCBI Official Synonym Symbols
''cytochrome P450; ALTERED TRYPTOPHAN REGULATION 4; ATR4; cytochrome P450; CYTOCHROME P450 MONOOXYGENASE 83B1; F3L17.70; F3L17_70; family 83; polypeptide 1; polypeptide 1''; RED ELONGATED 1; RED1; RNT1; RUNT 1; subfamily B; SUPERROOT 2; SUR2
NCBI Protein Information
cytochrome P450, family 83, subfamily B, polypeptide 1
NCBI Summary
Encodes an oxime-metabolizing enzyme in the biosynthetic pathway of glucosinolates. Is required for phytochrome signal transduction in red light. Mutation confers auxin overproduction.
UniProt Gene Name
CYP83B1
UniProt Synonym Gene Names
ATR4; RED1; RNT1; RUNT1; SUR2
UniProt Protein Name
Cytochrome P450 83B1
UniProt Synonym Protein Names
Protein ALTERED TRYPTOPHAN REGULATION 4; Protein RED ELONGATED 1; Protein SUPERROOT 2
UniProt Primary Accession #
O65782
UniProt Related Accession #
O65782
UniProt Comments
Involved in the metabolism of aromatic oximes. Catalyzes the oxime metabolizing step in indole glucosinolate biosynthesis by converting indole-3-acetaldoxime into indole-3-S-alkyl-thiohydroximate. Probably required for glucosinolate activation in response to pathogens. Functions in auxin homeostasis because indole-3-acetaldoxime also serves as a precursor for auxin biosynthesis. Specifically metabolizes (E)-p-hydroxyphenylacetaldoxime into an S-alkyl-thiohydroximate (PubMed:26361733).