NCBI Accession #
NP_180239.1
NCBI GenBank Nucleotide #
NM_128228.3
NCBI Official Full Name
PHYB activation tagged suppressor 1 protein
NCBI Official Symbol
BAS1
NCBI Official Synonym Symbols
CYP72B1; CYP734A1; F18A8.8; F18A8_8; PHYB ACTIVATION TAGGED SUPPRESSOR 1
NCBI Protein Information
PHYB activation tagged suppressor 1 protein
NCBI Summary
Encodes a member of the cytochrome p450 family that serves as a control point between multiple photoreceptor systems and brassinosteroid signal transduction. Involved in brassinolide metabolism. Mediates response to a variety of light signals including hypocotyl elongation and cotyledon expansion.
UniProt Gene Name
CYP734A1
UniProt Synonym Gene Names
BAS1
UniProt Protein Name
Cytochrome P450 734A1
UniProt Synonym Protein Names
Protein PHYB ACTIVATION-TAGGED SUPPRESSOR 1
UniProt Entry Name
C734A_ARATH
UniProt Primary Accession #
O48786
UniProt Related Accession #
O48786
UniProt Comments
Function: Cytochrome P450 involved in brassinosteroids (BRs) inactivation and regulation of BRs homeostasis. Inactivates the BRs castasterone and brassinolide through carbon 26 hydroxylation. Acts in association with CYP72C1 to inactivate BRs and modulate photomorphogenesis.Cofactor: Heme group By similarity.Subcellular location: Membrane; Single-pass membrane protein Potential. Induction: By brassinolide, auxin and dark treatment.Disruption phenotype: No visible phenotype under normal growth condition, but reduced responsiveness of hypocotyls to light and increased responsiveness to brassinolide. Strong reduction of C-26 hydroxylase activity.Miscellaneous: Plants overexpressing CYP734A1 exhibit severe dwarfism.Sequence similarities: Belongs to the cytochrome P450 family.