NCBI Accession #
NP_180996.1
NCBI GenBank Nucleotide #
NM_129001.3
NCBI Official Full Name
cytochrome P450, family 710, subfamily A, polypeptide 2
NCBI Official Symbol
CYP710A2
NCBI Official Synonym Symbols
cytochrome P450; F13P17.22; family 710; polypeptide 2; subfamily A
NCBI Protein Information
cytochrome P450, family 710, subfamily A, polypeptide 2
NCBI Summary
Encodes a protein with C22-sterol desaturase activity. The enzyme was shown to catalyze the conversion of both 24-epi-campesterol and β-sitosterol to brassicasterol and stigmasterol, respectively, in the presence of NADPH.
UniProt Gene Name
CYP710A2
UniProt Protein Name
Cytochrome P450 710A2
UniProt Synonym Protein Names
C-22 sterol desaturase
UniProt Primary Accession #
O64698
UniProt Secondary Accession #
Q8LE78
UniProt Related Accession #
O64698
UniProt Comments
Required to form the C-22 double bond in the sterol side chain. Possesses in vitro C-22 desaturase activity toward 24-epi-campesterol and beta-sitosterol and produces brassicasterol and stigmasterol, respectively. No activity with campesterol.