NCBI Accession #
NP_001032030.1
NCBI GenBank Nucleotide #
NM_001036953.1
NCBI Official Full Name
cytochrome P450, family 708, subfamily A, polypeptide 2
NCBI Official Symbol
CYP708A2
NCBI Official Synonym Symbols
''cytochrome P450; CYP708 A2; cytochrome P450; CYTOCHROME P450; family 708; FAMILY 708; MDN11.7; MDN11_7; polypeptide 2; POLYPEPTIDE 2; polypeptide 2''; subfamily A; SUBFAMILY A; THAH; THAH1; THALIANOL HYDROXYLASE; THALIANOL HYDROXYLASE 1
NCBI Protein Information
cytochrome P450, family 708, subfamily A, polypeptide 2
NCBI Summary
Encodes a member of the CYP708A family of cytochrome P450 enzymes. THAH appears to add a hydroxyl group to the triterpene thalianol. thah1 mutants have an elevated accumulation of thalianol. thah1-1 mutants have longer roots than wild type plants. Thalian-diol and desaturated thalian-diol are lost from the root extracts of thah1-1 mutants. Overexpression of the sequence from At5g48000.1 rescues the thah1-1 mutant phenotype (Field 2008); it is unknown whether the shorter sequences associated with other gene models would provide functional complementation.
UniProt Gene Name
CYP708A2
UniProt Synonym Gene Names
THAH; AtTHAH
UniProt Protein Name
Cytochrome P450 708A2
UniProt Synonym Protein Names
Thalianol hydroxylase; AtTHAH
UniProt Primary Accession #
Q8L7D5
UniProt Secondary Accession #
Q3E8E7; Q3E8E8; Q9FI38; B9DGZ3
UniProt Related Accession #
Q8L7D5
UniProt Comments
Hydroxylates thalianol into thalian-diol.