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Cyclin-dependent kinase A-1 (CDKA-1), Recombinant Protein
Cat: RP06622
Size: 0.02 mg (E-Coli)/ 0.02 mg (Yeast)/ 0.1 mg (E-Coli)/ 0.1 mg (Yeast)/ 0.02 mg (Baculovirus)/ 0.02 mg (Mammalian-Cell)/ 0.1 mg (Baculovirus)/ 1 mg (E-Coli)/ 1 mg (Yeast)/ 0.1 mg (Mammalian-Cell)/ 1 mg (Baculovirus)/ 0.5 mg (Mammalian-Cell)
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:
Product Info
Full Product Name
Recombinant Arabidopsis thaliana Cyclin-dependent kinase A-1 (CDKA-1)
Product Gene Name
CDKA-1 recombinant protein
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Sequence
MDQYEKVEKI GEGTYGVVYK ARDKVTNETI ALKKIRLEQE DEGVPSTAIR EISLLKEMQH SNIVKLQDVV HSEKRLYLVF EYLDLDLKKH MDSTPDFSKD LHMIKTYLYQ ILRGIAYCHS HRVLHRDLKP QNLLIDRRTN SLKLADFGLA RAFGIPVRTF THEVVTLWYR APEILLGSHH YSTPVDIWSV GCIFAEMISQ KPLFPGDSEI DQLFKIFRIM GTPYEDTWRG VTSLPDYKSA FPKWKPTDLE TFVPNLDPDG VDLLSKMLLM DPTKRINARA ALEHEYFKDL GGMP
Sequence Positions
1-294, Full length protein
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
34,030 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
Cyclin-dependent kinase
NCBI/Uniprot Data
NCBI Accession #
NP_566911.1
NCBI GI #
18408696
NCBI GenBank Nucleotide #
NM_114734.4
NCBI GeneID
824036
NCBI Official Full Name
cell division control 2
NCBI Official Symbol
CDC2
NCBI Official Synonym Symbols
CDC2A; CDC2AAT; CDK2; CDKA1; CDKA;1; cell division control 2; CYCLIN-DEPENDENT KINASE A;1; P34CDC2
NCBI Protein Information
cell division control 2
NCBI Summary
A-type cyclin-dependent kinase. Together with its specific inhibitor, the Kip-related protein, KRP2 they regulate the mitosis-to-endocycle transition during leaf development. Dominant negative mutations abolish cell division. Loss of function phenotype has reduced fertility with failure to transmit via pollen. Pollen development is arrested at the second mitotic division. Expression is regulated by environmental and chemical signals. Part of the promoter is responsible for expression in trichomes. Functions as a positive regulator of cell proliferation during development of the male gametophyte, embryo and endosperm. Phosphorylation of threonine 161 is required for activation of its associated kinase.
UniProt Gene Name
CDKA-1
UniProt Synonym Gene Names
CDC2; CDC2A; CDKA;1
UniProt Protein Name
Cyclin-dependent kinase A-1
UniProt Synonym Protein Names
Cell division control protein 2 homolog A
UniProt Primary Accession #
P24100
UniProt Secondary Accession #
Q29Q50; Q8RX68; Q9M307
UniProt Related Accession #
P24100; AAB22607
UniProt Comments
Involved in the control of the cell cycle. Essential for both G1/S and G2/M (mitosis) phase transitions. Functions in cell morphogenesis as well as cell proliferation. Required for cell division (entry into mitosis) of the generative cell in male gametogenesis. Required to trigger guard mother cells (GMC) symmetric divisions at the late stage of stomatal development, probably via the regulation of G1 to S transition in the cell cycle. Promotes divisions in the guard cells (GCs) after the guard mother cells (GMC) symmetric division when in the presence of CYCD3-2 (PubMed:24687979).
For research use only, not for clinical use.