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CST complex subunit CTC1 (CTC1), Recombinant Protein
Cat: RP02473
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:
Product Info
Full Product Name
Recombinant Arabidopsis thaliana CST complex subunit CTC1 (CTC1) , partial
Product Gene Name
CTC1 recombinant protein
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
74,072 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
CST complex
NCBI/Uniprot Data
NCBI Accession #
NP_001118960.1
NCBI GI #
186511635
NCBI GenBank Nucleotide #
NM_001125488.2
NCBI GeneID
826554
NCBI Official Full Name
conserved telomere maintenance component 1
NCBI Official Symbol
CTC1
NCBI Official Synonym Symbols
ATCTC1; conserved telomere maintenance component 1; F17A8.30; F17A8_30
NCBI Protein Information
conserved telomere maintenance component 1
NCBI Summary
Encodes CTC1 (Conserved Telomere Maintenance Component 1) involved in telomere maintenance.
UniProt Gene Name
CTC1
UniProt Synonym Gene Names
AtCTC1
UniProt Protein Name
CST complex subunit CTC1
UniProt Synonym Protein Names
Protein CONSERVED TELOMERE MAINTENANCE COMPONENT 1
UniProt Primary Accession #
D0EL35
UniProt Secondary Accession #
Q0WL26; Q9SZ84; B3H4T9
UniProt Related Accession #
D0EL35
UniProt Comments
Component of the CST complex, a complex that binds to single-stranded DNA and is required to protect telomeres from DNA degradation. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves (PubMed:19854131). Associates with enzymatically active telomerase (PubMed:25329641).
For research use only, not for clinical use.