NCBI Accession #
NP_849588.1
NCBI GenBank Nucleotide #
NM_179257.1
NCBI Official Full Name
cryptochrome 2
NCBI Official Symbol
CRY2
NCBI Official Synonym Symbols
AT-PHH1; ATCRY2; CRY2; cryptochrome 2; CRYPTOCHROME 2 APOPROTEIN; F19P19.14; F19P19_14; FHA; PHH1
NCBI Protein Information
cryptochrome 2
NCBI Summary
Blue light receptor mediating blue-light regulated cotyledon expansion and flowering time. Positive regulator of the flowering-time gene CONSTANS. This gene possesses a light-induced CNT2 N-terminal homodimerisation domain.Involved in blue-light induced stomatal opening. Involved in triggering chromatin decondensation. An 80-residue motif (NC80) is sufficient to confer CRY2's physiological function. It is proposed that the PHR domain and the C-terminal tail of the unphosphorylated CRY2 form a "closed" conformation to suppress the NC80 motif in the absence of light. In response to blue light, the C-terminal tail of CRY2 is phosphorylated and electrostatically repelled from the surface of the PHR domain to form an "open" conformation, resulting in derepression of the NC80 motif and signal transduction to trigger photomorphogenic responses. Cry2 phosphorylation and degradation both occur in the nucleus.
UniProt Synonym Gene Names
PHH1
UniProt Protein Name
Cryptochrome-2
UniProt Synonym Protein Names
Blue light photoreceptor
UniProt Entry Name
CRY2_ARATH
UniProt Primary Accession #
Q96524
UniProt Secondary Accession #
Q42549; Q42603; Q42604; Q56ZL8; Q696X6; Q696X8; Q696Z7; B0LQ23; B0LQ24; B0LQ25; B0LQ29
UniProt Related Accession #
Q96524