COP9 signalosome complex subunit 8 (CSN8), Recombinant Protein
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COP9 signalosome complex subunit 8 (CSN8), Recombinant Protein

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Cat: RP02517
Size: 0.02 mg (E-Coli)/ 0.1 mg (E-Coli)/ 0.02 mg (Yeast)/ 0.1 mg (Yeast)/ 0.02 mg (Baculovirus)/ 0.02 mg (Mammalian-Cell)/ 1 mg (E-Coli)/ 0.1 mg (Baculovirus)/ 1 mg (Yeast)/ 0.1 mg (Mammalian-Cell)/ 1 mg (Baculovirus)/ 0.5 mg (Mammalian-Cell)
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:

Product Info

Full Product Name
Recombinant Arabidopsis thaliana COP9 signalosome complex subunit 8 (CSN8)
Product Gene Name
CSN8 recombinant protein
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Sequence
MDLSPVKEAL AAKSFDKIAD ICDTLMLQVA SEGIEYHDDW PYAIHLLGYF YVDDCDSARF LWKRIPTAIK ERKPEVVAAW GIGQKLWTHD YAGVYEAIRG YDWSQEAKDM VAAFSDLYTK RMFQLLLSAY STITIHDLAL FLGMTEDDAT TYVVENGWTV DAASQMASVK KQAVKREQKV DSSKLQRLTE YVFHLEH
Sequence Positions
1-197, Full length protein
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
22,547 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.

NCBI/Uniprot Data

NCBI Accession #
NP_193147.1
NCBI GI #
15236410
NCBI GenBank Nucleotide #
NM_117488.4
NCBI GeneID
827049
NCBI Official Full Name
COP9 signalosome, subunit CSN8
NCBI Official Symbol
COP9
NCBI Official Synonym Symbols
CONSTITUTIVE PHOTOMORPHOGENIC 9; COP9 SIGNALOSOME SUBUNIT 8; CSN8; DL3095C; EMB143; EMBRYO DEFECTIVE 143; FCAALL.131; FUS7; FUSCA 7; FUSCA PROTEIN FUS7
NCBI Protein Information
COP9 signalosome, subunit CSN8
NCBI Summary
Represses photomorphogenesis and induces skotomorphogenesis in the dark. A component of the COP9 signalosome complex.
UniProt Gene Name
CSN8
UniProt Synonym Gene Names
COP9; FUS7; CSN complex subunit 8
UniProt Protein Name
COP9 signalosome complex subunit 8
UniProt Synonym Protein Names
Constitutive photomorphogenesis protein 9; Protein FUSCA 7
UniProt Primary Accession #
P43255
UniProt Secondary Accession #
Q8GWZ4
UniProt Related Accession #
P43255
UniProt Comments
Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes such as photomorphogenesis and auxin and jasmonate responses. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF. It is involved in repression of photomorphogenesis in darkness by regulating the activity of COP1-containing Ubl ligase complexes. The complex is also required for degradation of IAA6 by regulating the activity of the Ubl ligase SCF-TIR complex.

For research use only, not for clinical use.