COP9 signalosome complex subunit 4 (CSN4), Recombinant Protein
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COP9 signalosome complex subunit 4 (CSN4), Recombinant Protein

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Cat: RP02923
Size: 0.02 mg (E-Coli)/ 0.02 mg (Yeast)/ 0.1 mg (E-Coli)/ 0.1 mg (Yeast)/ 0.02 mg (Baculovirus)/ 0.02 mg (Mammalian-Cell)/ 0.1 mg (Baculovirus)/ 1 mg (E-Coli)/ 1 mg (Yeast)/ 0.1 mg (Mammalian-Cell)/ 1 mg (Baculovirus)/ 0.5 mg (Mammalian-Cell)
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:

Product Info

Full Product Name
Recombinant Arabidopsis thaliana COP9 signalosome complex subunit 4 (CSN4)
Product Gene Name
CSN4 recombinant protein
Product Synonym Gene Name
CSN4
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Sequence
MDEALTNASA IGDQRQKIEQ YKLILSSVLS SNDLLQAQRF IDHILSDDVP LVVSRQLLQS FAQELGRLEP ETQKEIAQFT LTQIQPRVVS FEEQALVIRE KLAGLYESEQ EWSKAAQMLS GIDLDSGMRA VDDNFKLSKC IQIARLYLED DDAVNAEAFI NKASFLVSNS QNEVLNLQYK VCYARILDMK RKFLEAALRY YGISQIEQRQ IGDEEIDENA LEQALSAAVT CTILAGAGPQ RSRVLATLYK DERCSKLKIY PILQKVYLER ILRRPEIDAF SEELRPHQKA SLPDKSTVLD RAMIEHNLLS ASKLYTNIRF DELGTLLAID PRKAEKIAAN MIGQDRMRGS IDQEEAVIHF EDDVEELQQW DQQISGLCQA LNDILDGMAK KGMSVPV
Sequence Positions
1-397, Full length protein
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
44,957 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
COP9 signalosome complex

NCBI/Uniprot Data

NCBI Accession #
NP_199111.1
NCBI GI #
15239134
NCBI GenBank Nucleotide #
NM_123663.3
NCBI GeneID
834312
NCBI Official Full Name
Proteasome component (PCI) domain protein
NCBI Official Symbol
COP8
NCBI Official Synonym Symbols
ATS4; CONSTITUTIVE PHOTOMORPHOGENIC 14; CONSTITUTIVE PHOTOMORPHOGENIC 8; COP14; COP9 SIGNALOSOME SUBUNIT 4; CSN4; EMB134; EMBRYO DEFECTIVE 134; FUS4; FUS8; FUSCA 4; FUSCA 8; MBD2.17; MBD2_17
NCBI Protein Information
Proteasome component (PCI) domain protein
NCBI Summary
encodes subunit 4 of COP9 signalosome complex. sequence is similar to a subunit of the 19S regulatory particle of the 26S proteasome. recessive mutation causes derepression of photomorphogenesis.
UniProt Gene Name
CSN4
UniProt Synonym Gene Names
COP8; FUS4; AtS4; Signalosome subunit 4
UniProt Protein Name
COP9 signalosome complex subunit 4
UniProt Synonym Protein Names
Constitutive photomorphogenesis protein 8; Protein FUSCA 4
UniProt Primary Accession #
Q8L5U0
UniProt Secondary Accession #
Q9FMM1; Q9SW74
UniProt Related Accession #
Q8L5U0
UniProt Comments
Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes such as photomorphogenesis and auxin and jasmonate responses. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF. It is involved in repression of photomorphogenesis in darkness by regulating the activity of COP1-containing Ubl ligase complexes. The complex is also required for degradation of IAA6 by regulating the activity of the Ubl ligase SCF-TIR complex.

For research use only, not for clinical use.