COP9 signalosome complex subunit 2 (CSN2), Recombinant Protein
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COP9 signalosome complex subunit 2 (CSN2), Recombinant Protein

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Cat: RP02401
Size: 0.02 mg (E-Coli)/ 0.02 mg (Yeast)/ 0.1 mg (E-Coli)/ 0.1 mg (Yeast)/ 0.02 mg (Baculovirus)/ 0.02 mg (Mammalian-Cell)/ 0.1 mg (Baculovirus)/ 1 mg (E-Coli)/ 0.1 mg (Mammalian-Cell)/ 1 mg (Yeast)/ 1 mg (Baculovirus)/ 0.5 mg (Mammalian-Cell)
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:

Product Info

Full Product Name
Recombinant Arabidopsis thaliana COP9 signalosome complex subunit 2 (CSN2)
Product Gene Name
CSN2 recombinant protein
Product Synonym Gene Name
CSN2
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Sequence
MASDADMEDY GFEYSDEEQE EQDVDIENQY YNSKGMVETE PEEALSGFAE VVQMEPEKAD WGFKALKQTV KIYYRLGKYK EMMEAYTEML TYIKSAVTRN YSEKCINNIM DFVSGSASQN TGLLQEFYQT TLKALEEAKN ERLWFKTNLK LCNIWFDIGE YRRMTKILKE LHKSCQKEDG TDDQKKGSQL LEVYAIEIQI YTETKDNKKL KQLYHKALAI KSAIPHPRIM GIIRECGGKM HMAERQWEEA ATDFFEAFKN YDEAGNQRRI QCLKYLVLAN MLMESEVNPF DGQEAKPYKN DPEILAMTNL IAAYQRNEII EFERILKSNR RTIMDDPFIR NYMEDLLKKV RTQVLLKLIK PYTKIGIPFI SKELNVPETD VTELLVSLIL DSRIDGHIDE MNRYLLRGDS GNGRKLHKAV DKWNSQLKSL SSNITSRVC
Sequence Positions
1-439, Full length protein
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
51,186 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
COP9 signalosome complex

NCBI/Uniprot Data

NCBI Accession #
NP_565632.1
NCBI GI #
18401293
NCBI GenBank Nucleotide #
NM_128257.4
NCBI GeneID
817241
NCBI Official Full Name
proteasome family protein
NCBI Official Symbol
FUS12
NCBI Official Synonym Symbols
ATCSN2; CONSTITUTIVE PHOTOMORPHOGENIC 12; COP12; CSN2; FUSCA 12; T20P8.4; T20P8_4
NCBI Protein Information
proteasome family protein
NCBI Summary
Represses photomorphogenesis and induces skotomorphogenesis in the dark.
UniProt Gene Name
CSN2
UniProt Synonym Gene Names
FUS12; Signalosome subunit 2
UniProt Protein Name
COP9 signalosome complex subunit 2
UniProt Synonym Protein Names
Protein FUSCA 12
UniProt Primary Accession #
Q8W207
UniProt Secondary Accession #
Q94A24; Q9ZVD8
UniProt Related Accession #
Q8W207
UniProt Comments
Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes such as photomorphogenesis and auxin and jasmonate responses. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF. It is involved in repression of photomorphogenesis in darkness by regulating the activity of COP1-containing Ubl ligase complexes. The complex is also required for degradation of IAA6 by regulating the activity of the Ubl ligase SCF-TIR complex.

For research use only, not for clinical use.