NCBI Accession #
NP_566459.2
NCBI GenBank Nucleotide #
NM_112201.5
NCBI Official Full Name
Ubiquitin-conjugating enzyme family protein
NCBI Official Symbol
FUS9
NCBI Official Synonym Symbols
CIN4; CONSTITUTIVE PHOTOMORPHOGENIC 10; COP10; CYTOKININ-INSENSITIVE 4; E2 UBIQUITIN-CONJUGATING ENZYME; EMB144; EMBRYO DEFECTIVE 144; FUSCA 9
NCBI Protein Information
Ubiquitin-conjugating enzyme family protein
NCBI Summary
Encodes a protein similar to ubiquitin-conjugating enzyme (E2) variant proteins (UEV); lacks catalytic cysteine residue found in ubiquitin-conjugating enzyme E2. Represses photomorphogenesis and induces skotomorphogenesis in the dark.
UniProt Protein Name
Constitutive photomorphogenesis protein 10
UniProt Primary Accession #
Q9LJD7
UniProt Related Accession #
Q9LJD7
UniProt Comments
Component of light signal transduction machinery. Involved in repression of photomorphogenesis in darkness by participating in the CDD complex, a complex probably required to regulate the activity of ubiquitin conjugating enzymes (E2s). Repression of photomorphogenesis is probably mediated by ubiquitination and subsequent degradation of photomorphogenesis-promoting factors such as HY5, HYH and LAF1. Although strongly related to ubiquitin-conjugating enzyme, it has no catalytic activity by itself due to the absence of the conserved Cys active site at position 120. It can however enhance the activity of E2 conjugating enzymes.