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Cleavage and polyadenylation specificity factor subunit 2 (CPSF100), Recombinant Protein
Cat: RP08576
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:
Product Info
Full Product Name
Recombinant Arabidopsis thaliana Cleavage and polyadenylation specificity factor subunit 2 (CPSF100) , partial
Product Gene Name
CPSF100 recombinant protein
Product Synonym Gene Name
CPSF100
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
82,139 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
Cleavage and polyadenylation specificity factor
NCBI/Uniprot Data
NCBI Accession #
NP_197776.1
NCBI GI #
15237845
NCBI GenBank Nucleotide #
NM_122293.4
NCBI GeneID
832453
NCBI Official Full Name
cleavage and polyadenylation specificity factor 100
NCBI Official Symbol
CPSF100
NCBI Official Synonym Symbols
ATCPSF100; CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR; cleavage and polyadenylation specificity factor 100; CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR 100; EMB1265; EMBRYO DEFECTIVE 1265; ENHANCED SILENCING PHENOTYPE 5; ESP5
NCBI Protein Information
cleavage and polyadenylation specificity factor 100
NCBI Summary
Encodes a protein similar to the 100kD subunit of cleavage and polyadenylation specificity factor (CPSF), the factor responsible for the recognition of the AAUAAA motif during mRNA polyadenylation. The protein interacts with a portion of a nuclear poly(A) polymerase. It is likely to be a part of the mRNA 3'end formation apparatus.
UniProt Gene Name
CPSF100
UniProt Synonym Gene Names
; AtCPSF100; CPSF 100 kDa subunit
UniProt Protein Name
Cleavage and polyadenylation specificity factor subunit 2
UniProt Synonym Protein Names
Cleavage and polyadenylation specificity factor 100 kDa subunit; AtCPSF100; CPSF 100 kDa subunit; Protein EMBRYO DEFECTIVE 1265; Protein ENHANCED SILENCING PHENOTYPE 5
UniProt Primary Accession #
Q9LKF9
UniProt Secondary Accession #
Q9FF92
UniProt Related Accession #
Q9LKF9
UniProt Comments
CPSF plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A)polymerase and other factors to bring about cleavage and poly(A) addition . Required for antisense-RNA-mediated gene silencing (PubMed:17008405).
For research use only, not for clinical use.