Cleavage and polyadenylation specificity factor CPSF30 (CPSF30), Recombinant Protein
  1. Home
  2. Products
  3. Plant Proteins
  4. Recombinant Plant Proteins
  5. Recombinant Arabidopsis Thaliana Protein
Products
Online Inquiry

Cleavage and polyadenylation specificity factor CPSF30 (CPSF30), Recombinant Protein

Inquiry
Cat: RP06886
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:

Product Info

Full Product Name
Recombinant Arabidopsis thaliana Cleavage and polyadenylation specificity factor CPSF30 (CPSF30) , partial
Product Gene Name
CPSF30 recombinant protein
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
27,969 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
30-kDa cleavage and polyadenylation specificity factor

NCBI/Uniprot Data

NCBI Accession #
NP_174334.2
NCBI GI #
79356321
NCBI GenBank Nucleotide #
NM_102782.4
NCBI GeneID
839925
NCBI Official Full Name
cleavage and polyadenylation specificity factor 30
NCBI Official Symbol
CPSF30
NCBI Official Synonym Symbols
ARABIDOPSIS THALIANA CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR 30; ATCPSF30; cleavage and polyadenylation specificity factor 30; F26G16.6; F26G16_6
NCBI Protein Information
cleavage and polyadenylation specificity factor 30
NCBI Summary
Encodes AtCPSF30, the 30-KDa subunit of cleavage and polyadenylation specificity factor. AtCPSF30 is a probable processing endonuclease. Nucleus-localized RNA binding protein capable of interacting with itself and with calmodulin. Its RNA-binding activity is inhibited by calmodulin in a calcium-dependent fashion.
UniProt Gene Name
CPSF30
UniProt Synonym Gene Names
AtC3H11
UniProt Protein Name
30-kDa cleavage and polyadenylation specificity factor 30
UniProt Synonym Protein Names
Protein OXIDATIVE STRESS TOLERANT 6
UniProt Primary Accession #
A9LNK9
UniProt Secondary Accession #
Q9S9Q5; Q9S9Q6
UniProt Related Accession #
A9LNK9
UniProt Comments
Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation. May interact with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition . Mediates poly(A) site selection (PubMed:23136375). Binds RNA in a calcium-dependent manner (PubMed:16500995, PubMed:17576667, PubMed:20214900). Exhibits endonuclease activity with an ability to nick and degrade linear as well as circular single-stranded RNA that leaves RNA 3' ends with hydroxyl groups, thus mediating processing of the pre-mRNA as a prelude to the polyadenylation (PubMed:17576667). Involved in the post-transcriptional control, probably via poly(A) addition, of the responses of plants to stress, especially genes mediating tolerance to oxidative stress (PubMed:18545667). Plays a role in the regulation of salicylic acid (SA) production via the control of messenger RNA 3' end processing, thus being a key component of programmed cell death and plant immune responses required for resistance to virulent Pseudomonas syringae pv tomato DC3000 (Pst) (PubMed:24706550).

For research use only, not for clinical use.