NCBI Accession #
NP_201279.1
NCBI GenBank Nucleotide #
NM_125870.3
NCBI Official Full Name
cellulose synthase 6
NCBI Official Symbol
CESA6
NCBI Official Synonym Symbols
cellulose synthase 6; E112; ISOXABEN RESISTANT 2; IXR2; MVP7.7; MVP7_7; PRC1; PROCUSTE 1
NCBI Protein Information
cellulose synthase 6
NCBI Summary
Encodes a cellulose synthase isomer. CESA6 mutants have cellulose defect in the primary cell wall. Multiple lines of evidence suggest that CESA6, along with CESA1 and CESA3 are present in the same plasma membrane complex for cellulose biosynthesis. CESA2 and CESA5 are related to CESA6, having partially redundant roles. As inferred from the null role of secondary wall-type CesAs, included in a set of five primary wall-type CesAs that may support trichome cell wall thickening.
UniProt Synonym Gene Names
IXR2; PRC1; QUI; AtCesA6
UniProt Protein Name
Cellulose synthase A catalytic subunit 6 [UDP-forming]
UniProt Synonym Protein Names
AraxCelA; Isoxaben-resistant protein 2; Protein PROCUSTE 1; Protein QUILL
UniProt Primary Accession #
Q94JQ6
UniProt Secondary Accession #
O65338; Q0WNG4; Q9FGF9
UniProt Related Accession #
Q94JQ6
UniProt Comments
Catalytic subunit of cellulose synthase terminal complexes ('rosettes'), required for beta-1,4-glucan microfibril crystallization, a major mechanism of the cell wall formation. Involved in the primary cell wall formation. The presence of each protein CESA1 and CESA6 is critical for cell expansion. The hypocotyl elongation is based on a CESA6-dependent cell elongation in dark and a CESA6-independent cell elongation in light. The transition between these two mechanisms requires photosynthesis and PHYB, but not CRY1. The CESA6-dependent cell elongation seems to be independent of gibberellic acid, auxin and ethylene. May be involved in sensitivity to isoxaben. Associates with and moves along cortical microtubules for the process of cellulose deposition.