NCBI Accession #
NP_849994.1
NCBI GenBank Nucleotide #
NM_179663.3
NCBI Official Full Name
CDC27 family protein
NCBI Official Synonym Symbols
CDC27b; HOBBIT; T2G17.20; T2G17_20
NCBI Protein Information
CDC27 family protein
NCBI Summary
Required for cell division and cell differentiation in meristems. Encodes a homolog of the CDC27 subunit of the anaphase-promoting complex (APC). Unlike other CDC27 homologs in Arabidopsis, its transcription is cell cycle regulated. Strong hbt mutants give rise to seedlings that lack an anatomically recognizable quiescent center and differentiated columella root cap cells, the cell types derived from the wild-type hypophysis. Furthermore, they have no mitotically active root meristem and lack a differentiated lateral root cap.
UniProt Synonym Gene Names
HBT; CDC27 homolog B
UniProt Protein Name
Cell division cycle protein 27 homolog B
UniProt Synonym Protein Names
Protein HOBBIT
UniProt Primary Accession #
Q8LGU6
UniProt Secondary Accession #
Q8W4M8; Q9SL81
UniProt Related Accession #
Q8LGU6
UniProt Comments
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex controls several key steps in the cell cycle by mediating ubiquitination and subsequent degradation of target proteins such as cyclins. The APC/C complex is required for the female gametophyte development and is involved in several aspect of development by controlling cell division and cell elongation. Involved in the control of endoreduplication. Functionally redundant with CDC27A in the control of gametophyte development.