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Cell cycle checkpoint protein RAD17 (RAD17), Recombinant Protein
Cat: RP05787
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:
Product Info
Full Product Name
Recombinant Arabidopsis thaliana Cell cycle checkpoint protein RAD17 (RAD17) , partial
Product Gene Name
RAD17 recombinant protein
Product Synonym Gene Name
RAD17
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
66,819 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
Checkpoint protein
NCBI/Uniprot Data
NCBI Accession #
NP_201414.1
NCBI GI #
15239269
NCBI GenBank Nucleotide #
NM_126011.2
NCBI GeneID
836745
NCBI Official Full Name
RADIATION SENSITIVE 17
NCBI Official Symbol
ATRAD17
NCBI Official Synonym Symbols
K2A18.21; K2A18_21; RAD17; RADIATION SENSITIVE 17
NCBI Protein Information
RADIATION SENSITIVE 17
NCBI Summary
Encodes a homolog to yeast RAD17. Involved in the regulation of DNA damage repair and homologous recombination. Mutant has increased sensitivity to MMS and increased telomere lengths.
UniProt Gene Name
RAD17
UniProt Synonym Gene Names
AtRAD17
UniProt Protein Name
Cell cycle checkpoint protein RAD17
UniProt Synonym Protein Names
Radiation-sensitive protein 17
UniProt Primary Accession #
Q9MBA3
UniProt Related Accession #
Q9MBA3
UniProt Comments
Seems to be involved in regulation of DNA repair correlated to non-homologous double strand breaks (DSBs) repair. In vitro, involved in rapid but not in slow DSB repair mechanism. Required for effective immune responses that involve activation of DNA damage responses (PubMed:24207055).
For research use only, not for clinical use.