NCBI Accession #
NP_176967.1
NCBI GenBank Nucleotide #
NM_105470.3
NCBI Official Full Name
phosphatidylinositol synthase 1
NCBI Official Symbol
PIS1
NCBI Official Synonym Symbols
ATPIS; ATPIS1; PHOSPHATIDYLINOSITOL SYNTHASE; phosphatidylinositol synthase 1; T23K23.15; T23K23_15
NCBI Protein Information
phosphatidylinositol synthase 1
UniProt Synonym Gene Names
AtPIS1; PI synthase 1; PtdIns synthase 1
UniProt Protein Name
CDP-diacylglycerol--inositol 3-phosphatidyltransferase 1
UniProt Synonym Protein Names
Phosphatidylinositol synthase 1; AtPIS1; PI synthase 1; PtdIns synthase 1
UniProt Primary Accession #
Q8LBA6
UniProt Secondary Accession #
O81846
UniProt Related Accession #
Q8LBA6
UniProt Comments
Catalyzes the biosynthesis of phosphatidylinositol (PtdIns) as well as PtdIns:inositol exchange reaction. May thus act to reduce an excessive cellular PtdIns content. The exchange activity is due to the reverse reaction of PtdIns synthase and is dependent on CMP, which is tightly bound to the enzyme.