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CBL-interacting serine/threonine-protein kinase 23 (CIPK23), Recombinant Protein
Cat: RP07120
Size: 0.02 mg (E-Coli)/ 0.02 mg (Yeast)/ 0.1 mg (E-Coli)/ 0.1 mg (Yeast)/ 0.02 mg (Baculovirus)/ 0.02 mg (Mammalian-Cell)/ 0.1 mg (Baculovirus)/ 1 mg (E-Coli)/ 0.1 mg (Mammalian-Cell)/ 1 mg (Yeast)/ 1 mg (Baculovirus)/ 0.5 mg (Mammalian-Cell)
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:
Product Info
Full Product Name
Recombinant Arabidopsis thaliana CBL-interacting serine/threonine-protein kinase 23 (CIPK23)
Product Gene Name
CIPK23 recombinant protein
Product Synonym Gene Name
CIPK23
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Sequence
MASRTTPSRS TPSRSTPSGS SSGGRTRVGK YELGRTLGEG TFAKVKFARN VENGDNVAIK VIDKEKVLKN KMIAQIKREI STMKLIKHPN VIRMFEVMAS KTKIYFVLEF VTGGELFDKI SSNGRLKEDE ARKYFQQLIN AVDYCHSRGV YHRDLKPENL LLDANGALKV SDFGLSALPQ QVREDGLLHT TCGTPNYVAP EVINNKGYDG AKADLWSCGV ILFVLMAGYL PFEDSNLTSL YKKIFKAEFT CPPWFSASAK KLIKRILDPN PATRITFAEV IENEWFKKGY KAPKFENADV SLDDVDAIFD DSGESKNLVV ERREEGLKTP VTMNAFELIS TSQGLNLGSL FEKQMGLVKR KTRFTSKSSA NEIVTKIEAA AAPMGFDVKT NNYKMKLTGE KSGRKGQLAV ATEVFQVAPS LYMVEMRKSG GDTLEFHKFY KNLTTGLKDI VWKTIDEEKE EGTDGGGTNG AMANRTIAKQ ST
Sequence Positions
1-482, Full length protein
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
53,514 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
CBL-interacting protein kinase
NCBI/Uniprot Data
NCBI Accession #
NP_564353.1
NCBI GI #
18397430
NCBI GenBank Nucleotide #
NM_102766.6
NCBI GeneID
839907
NCBI Official Full Name
CBL-interacting protein kinase 23
NCBI Official Symbol
CIPK23
NCBI Official Synonym Symbols
ATCIPK23; CBL-interacting protein kinase 23; F12P21.6; F12P21_6; LKS1; LOW-K+-SENSITIVE 1; PKS17; SNF1-RELATED PROTEIN KINASE 3.23; SnRK3.23; SOS2-like protein kinase 17
NCBI Protein Information
CBL-interacting protein kinase 23
NCBI Summary
Arabidopsis thaliana CBL-interacting protein kinase 23. CIPK23 serves as a positive regulator of the potassium transporter AKT1 by directly phosphorylating AKT1. CIPK23 is activated by the binding of two calcineurin B-like proteins, CBL1 and CBL9.
UniProt Gene Name
CIPK23
UniProt Synonym Gene Names
LKS1; PKS17; SnRK3.23
UniProt Protein Name
CBL-interacting serine/threonine-protein kinase 23
UniProt Synonym Protein Names
Protein LOW-K(+)-SENSITIVE 1; SNF1-related kinase 3.23; SOS2-like protein kinase PKS17
UniProt Primary Accession #
Q93VD3
UniProt Secondary Accession #
Q9C753
UniProt Related Accession #
Q93VD3
UniProt Comments
CIPK serine-threonine protein kinases interact with CBL proteins. Binding of a CBL protein to the regulatory NAF domain of CIPK protein leads to activation of the kinase in a calcium-dependent manner. Downstream of CBL1, CBL2, CBL3 and CBL9, regulates by phosphorylation the K+ conductance and uptake of AKT1 in low K+ condition, in response to calcium signaling and during the stomatal opening regulation by monitoring the turgor pressure in guard cells. In response to low nitrate concentration, phosphorylates NRT1.1, switching it from a low-affinity nitrate transporter to a high-affinity transporter. Confers tolerance to low potassium conditions. Involved in drought sensitivity and leaf transpiration.
For research use only, not for clinical use.