CBL-interacting serine/threonine-protein kinase 11 (CIPK11), Recombinant Protein
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CBL-interacting serine/threonine-protein kinase 11 (CIPK11), Recombinant Protein

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Cat: RP06649
Size: 0.02 mg (E-Coli)/ 0.02 mg (Yeast)/ 0.1 mg (E-Coli)/ 0.1 mg (Yeast)/ 0.02 mg (Baculovirus)/ 0.02 mg (Mammalian-Cell)/ 0.1 mg (Baculovirus)/ 1 mg (E-Coli)/ 0.1 mg (Mammalian-Cell)/ 1 mg (Yeast)/ 1 mg (Baculovirus)/ 0.5 mg (Mammalian-Cell)
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:

Product Info

Full Product Name
Recombinant Arabidopsis thaliana CBL-interacting serine/threonine-protein kinase 11 (CIPK11)
Product Gene Name
CIPK11 recombinant protein
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Sequence
MPEIEIAAGS GDNNDALFGK YELGKLLGCG AFAKVFHARD RRTGQSVAVK ILNKKKLLTN PALANNIKRE ISIMRRLSHP NIVKLHEVMA TKSKIFFAME FVKGGELFNK ISKHGRLSED LSRRYFQQLI SAVGYCHARG VYHRDLKPEN LLIDENGNLK VSDFGLSALT DQIRPDGLLH TLCGTPAYVA PEILSKKGYE GAKVDVWSCG IVLFVLVAGY LPFNDPNVMN MYKKIYKGEY RFPRWMSPDL KRFVSRLLDI NPETRITIDE ILKDPWFVRG GFKQIKFHDD EIEDQKVESS LEAVKSLNAF DLISYSSGLD LSGLFAGCSN SSGESERFLS EKSPEMLAEE VEGFAREENL RMKKKKEEEY GFEMEGQNGK FGIGICISRL NDLLVVVEAR RRGGDGDCYK EMWNGKLRVQ LIRVCDQTSS TNAAI
Sequence Positions
1-435, Full length protein
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
49,017 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
CBL-interacting protein kinase

NCBI/Uniprot Data

NCBI Accession #
NP_180595.1
NCBI GI #
15227739
NCBI GenBank Nucleotide #
NM_128589.2
NCBI GeneID
817586
NCBI Official Full Name
SOS3-interacting protein 4
NCBI Official Symbol
SIP4
NCBI Official Synonym Symbols
CBL-INTERACTING PROTEIN KINASE 11; CIPK11; PKS5; PROTEIN KINASE SOS2-LIKE 5; SNF1-RELATED PROTEIN KINASE 3.22; SNRK3.22; SOS3-interacting protein 4; T9D9.17; T9D9_17
NCBI Protein Information
SOS3-interacting protein 4
NCBI Summary
Encodes a SOS2-like protein kinase that is a member of the CBL-interacting protein kinase family.Loss of function mutants show a decrease in sensitivity to high pH.Phosphorylates AHA2, a plasma membrane H+ ATPase.This phosphorylation appears to regulate the activity of the proton transporter.
UniProt Gene Name
CIPK11
UniProt Synonym Gene Names
PKS5; SIP4; SnRK3.22
UniProt Protein Name
CBL-interacting serine/threonine-protein kinase 11
UniProt Synonym Protein Names
SNF1-related kinase 3.22; SOS2-like protein kinase PKS5; SOS3-interacting protein 4
UniProt Primary Accession #
O22932
UniProt Secondary Accession #
Q7FYB7; Q944I6
UniProt Related Accession #
O22932
UniProt Comments
CIPK serine-threonine protein kinases interact with CBL proteins. Binding of a CBL protein to the regulatory NAF domain of CIPK protein lead to the activation of the kinase in a calcium-dependent manner. Acts as a negative regulator of the plasma membrane proton pump AHA2 by preventing its interaction with 14-3-3 protein.

For research use only, not for clinical use.