Calmodulin-binding transcription activator 3 (CMTA3), Recombinant Protein

Full Product Name

Recombinant Arabidopsis thaliana Calmodulin-binding transcription activator 3 (CMTA3) , partial

Product Gene Name

CMTA3 recombinant protein

Product Synonym Gene Name

CMTA3

Purity

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Molecular Weight

116,111 Da

Storage

Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.

Protein Family

Calmodulin-binding transcription activator

NCBI Accession #

NP_001118361.1

NCBI GI #

186502240

NCBI GenBank Nucleotide #

NM_001124889.2

NCBI GeneID

816762

NCBI Official Full Name

signal responsive 1

NCBI Official Symbol

SR1

NCBI Official Synonym Symbols

CALMODULIN-BINDING TRANSCRIPTION ACTIVATOR 3; CAMTA3; signal responsive 1; T26C19.4; T26C19_4

NCBI Protein Information

signal responsive 1

NCBI Summary

Encodes a putative CAM binding transcription factor. Loss of function mutations show enhanced resistance to fungal and bacterial pathogens suggesting that CAMTA functions to suppress defense responses.

UniProt Gene Name

CAMTA3

UniProt Synonym Gene Names

AtSR1

UniProt Protein Name

Calmodulin-binding transcription activator 3

UniProt Synonym Protein Names

Ethylene-induced calmodulin-binding protein 1

UniProt Primary Accession #

Q8GSA7

UniProt Secondary Accession #

Q0WW70; Q9FPR9; Q9SID7

UniProt Related Accession #

Q8GSA7

UniProt Comments

Transcription activator that binds to the DNA consensus sequence 5'-[ACG]CGCG[GTC]-3'. Binds calmodulin in a calcium-dependent manner in vitro (PubMed:12218065). Regulates transcriptional activity in response to calcium signals (Probable). Involved in freezing tolerance in association with CAMTA1 and CAMTA2 (PubMed:23581962). Required for the cold-induced expression of DREB1B/CBF1, DREB1C/CBF2, ZAT12 and GOLS3 (PubMed:19270186). Involved in response to cold. Contributes together with CAMTA5 to the positive regulation of the cold-induced expression of DREB1A/CBF3, DREB1B/CBF1 and DREB1C/CBF2 (PubMed:28351986). Involved together with CAMTA2 and CAMTA4 in the positive regulation of a general stress response (GSR) (PubMed:25039701). Involved in the regulation of GSR amplitude downstream of MEKK1 (PubMed:25157030). Involved in the regulation of a set of genes involved in defense responses against pathogens (PubMed:18298954). Involved in the regulation of both basal resistance and systemic acquired resistance (SAR) (PubMed:21900483). Acts as negative regulator of plant immunity (PubMed:19122675, PubMed:21900483, PubMed:22345509, PubMed:28407487). Binds to the promoter of the defense-related gene EDS1 and represses its expression (PubMed:19122675). Binds to the promoter of the defense-related gene NDR1 and represses its expression (PubMed:22345509). Involved in defense against insects (PubMed:23072934, PubMed:22371088). Required for tolerance to the generalist herbivore Trichoplusia ni, and contributes to the positive regulation of genes associated with glucosinolate metabolism (PubMed:23072934). Required for tolerance to Bradysia impatiens larvae. Mediates herbivore-induced wound response (PubMed:22371088). Required for wound-induced jasmonate accumulation (PubMed:23072934, PubMed:22371088). Involved in the regulation of ethylene-induced senescence by binding to the promoter of the senescence-inducer gene EIN3 and repressing its expression (PubMed:22345509).