NCBI Accession #
NP_200374.1
NCBI GenBank Nucleotide #
NM_124945.4
NCBI Official Full Name
two-pore potassium channel 1
NCBI Official Symbol
ATKCO1
NCBI Official Synonym Symbols
ATTPK1; CA2+ ACTIVATED OUTWARD RECTIFYING K+ CHANNEL 1; KCO1; MDF20.7; MDF20_7; TANDEM PORE K+ CHANNEL 1; TPK1; TWO PORE K CHANNEL; TWO PORE K CHANNEL 1
NCBI Protein Information
two-pore potassium channel 1
UniProt Synonym Gene Names
KCO1; AtTPK1; AtKCO1
UniProt Protein Name
Two-pore potassium channel 1
UniProt Synonym Protein Names
Calcium-activated outward-rectifying potassium channel 1; AtKCO1
UniProt Entry Name
KCO1_ARATH
UniProt Primary Accession #
Q8LBL1
UniProt Secondary Accession #
O04718; Q0WNY4; Q9FM75
UniProt Related Accession #
Q8LBL1
UniProt Comments
Voltage-independent, large conductance and potassium-selective tonoplast ion channel. Regulated by cytoplasmic calcium and pH. Does not mediate slow-vacuolar (SV) ionic currents, but essential to establish VK currents. Has some permeability for Rb+ and NH4+, but none for Na+, Cs+ or Li+. Involved in intracellular K+ redistribution and/or K+ retranslocation between different tissues.