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Bifunctional dihydrofolate reductase-thymidylate synthase (DRTS), Recombinant Protein
Cat: RP10433
Species: Zea mays (Maize)
Datasheet:
Product Info
Full Product Name
Recombinant Zea mays Bifunctional dihydrofolate reductase-thymidylate synthase (DRTS), partial
Product Gene Name
DRTS recombinant protein
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
58,966 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
NCBI/Uniprot Data
NCBI Accession #
NP_001104916.1
NCBI GI #
162464289
NCBI GenBank Nucleotide #
NM_001111446.1
NCBI GeneID
541707
NCBI Official Symbol
DRTS
NCBI Official Synonym Symbols
DHFR-TS; GRMZM2G005990
NCBI Protein Information
bifunctional dihydrofolate reductase-thymidylate synthase
UniProt Gene Name
DRTS
UniProt Synonym Gene Names
DHFR-TS
UniProt Protein Name
Bifunctional dihydrofolate reductase-thymidylate synthase
UniProt Primary Accession #
O81395
UniProt Related Accession #
O81395
UniProt Comments
Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism. Can play two different roles depending on the source of dihydrofolate: de novo synthesis of tetrahydrofolate or recycling of the dihydrofolate released as one of the end products of the TS catalyzed reaction. Catalyzes an essential reaction for de novo glycine and purine synthesis, DNA precursor synthesis, and for the conversion of dUMP to dTMP .
For research use only, not for clinical use.