Products
Online Inquiry
Auxin efflux carrier component 2 (PIN2), Recombinant Protein
Cat: RP03418
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:
Product Info
Full Product Name
Recombinant Arabidopsis thaliana Auxin efflux carrier component 2 (PIN2) , partial
Product Gene Name
PIN2 recombinant protein
Product Synonym Gene Name
PIN2
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
69,331 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
Auxin efflux carrier component
NCBI/Uniprot Data
NCBI Accession #
NP_568848.1
NCBI GI #
18423936
NCBI GenBank Nucleotide #
NM_125091.4
NCBI GeneID
835813
NCBI Official Full Name
Auxin efflux carrier family protein
NCBI Official Symbol
EIR1
NCBI Official Synonym Symbols
AGR; AGR1; AGRAVITROPIC ROOT; AGRAVITROPIC ROOT 1; ARABIDOPSIS THALIANA PIN-FORMED 2; ATPIN2; AUXIN TRANSPORT PROTEIN EIR1; ETHYLENE INSENSITIVE ROOT 1; MM31; MUL3.3; MUL3_3; PIN-FORMED 2; PIN2; POLAR-AUXIN-TRANSPORT EFFLUX COMPONENT AGRAVITROPIC 1; WAV6;
NCBI Protein Information
Auxin efflux carrier family protein
NCBI Summary
Encodes an auxin efflux carrier that is similar to bacterial membrane transporters. Root-specific role in the transport of auxin. Acts downstream of CTR1 and ethylene biosynthesis, in the same pathway as EIN2 and AUX1, and independent from EIN3 and EIN5/AIN1 pathway. In the root, the protein localizes apically in epidermal and lateral root cap cells and predominantly basally in cortical cells. Functions may be regulated by phosphorylation status. EIR1 expression is induced by brassinolide treatment in the brassinosteroid-insensitive br1 mutant. Gravistimulation resulted in asymmetric PIN2 distribution, with more protein degraded at the upper side of the gravistimulated root. Protein turnover is affected by the proteasome and by endosomal cycling. Plasma membrane-localized PIN proteins mediate a saturable efflux of auxin. PINs mediate auxin efflux from mammalian and yeast cells without needing additional plant-specific factors. The action of PINs in auxin efflux is distinct from PGPs, rate-limiting, specific to auxins and sensitive to auxin transport inhibitors. Membrane sterol composition is essential for the acquisition of PIN2 polarity.
UniProt Gene Name
PIN2
UniProt Synonym Gene Names
AtAGR1
UniProt Protein Name
Auxin efflux carrier component 2
UniProt Synonym Protein Names
Auxin efflux carrier AGR
UniProt Primary Accession #
Q9LU77
UniProt Secondary Accession #
O82810; Q9SYT2
UniProt Related Accession #
Q9LU77
UniProt Comments
Acts as a component of the auxin efflux carrier. Seems to be involved in the root-specific auxin transport, and mediates the root gravitropism. Its particular localization suggest a role in the translocation of auxin towards the elongation zone.
For research use only, not for clinical use.