NCBI Accession #
NP_085503.1
NCBI GenBank Nucleotide #
NC_001284.2
NCBI Official Full Name
ATPase subunit 6 (mitochondrion)
NCBI Official Symbol
atp6-1
NCBI Protein Information
ATPase subunit 6
UniProt Protein Name
ATP synthase subunit a-1
UniProt Synonym Protein Names
F-ATPase protein 6; P6-1
UniProt Primary Accession #
P93298
UniProt Secondary Accession #
A7KNE5; F4INF7
UniProt Comments
Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F1 - containing the extramembraneous catalytic core and F0 - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Key component of the proton channel; it may play a direct role in the translocation of protons across the membrane .