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ATP-dependent DNA helicase Q-like 2 (RECQL2), Recombinant Protein
Cat: RP07115
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:
Product Info
Full Product Name
Recombinant Arabidopsis thaliana ATP-dependent DNA helicase Q-like 2 (RECQL2) , partial
Product Gene Name
RECQL2 recombinant protein
Product Synonym Gene Name
RECQL2
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
65,651 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
NCBI/Uniprot Data
NCBI Accession #
NP_001077639.1
NCBI GI #
145324100
NCBI GenBank Nucleotide #
NM_001084170.2
NCBI GeneID
840026
NCBI Official Full Name
RECQ helicase L2
NCBI Official Symbol
RECQL2
NCBI Official Synonym Symbols
ARABIDOPSIS THALIANA RECQ 2; ARABIDOPSIS THALIANA RECQ 2; ATRECQ2; MED34; RECQ helicase L2; T19E23.16; T19E23_16
NCBI Protein Information
RECQ helicase L2
NCBI Summary
Encodes a (d)NTP-dependent 3'->5' DNA helicase. This protein can also disrupt D loop structures and may mediate branch migration of Holliday junctions when tested in vitro. The unwinding activity of the enzyme depends on the presence of divalent cations (Mg2+, Mn2+, or Ca2+, but not Zn2+).(d)NTPs are also required with ATP and dATP supporting the greatest amount of DNA unwinding in vitro.
UniProt Gene Name
MED34
UniProt Synonym Gene Names
MED34_1; RECQ2; RECQL2; RQL2; AtRecQ2; AtRecQl2
UniProt Protein Name
Mediator of RNA polymerase II transcription subunit 34
UniProt Synonym Protein Names
ATP-dependent DNA helicase Q-like 2 (EC:3.6.4.12); RecQ-like protein 2; AtRecQ2; AtRecQl2
UniProt Primary Accession #
Q9FT73
UniProt Secondary Accession #
Q9SHE4; A8MRK2
UniProt Related Accession #
Q9FT73
UniProt Comments
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. The Mediator complex, having a compact conformation in its free form, is recruited to promoters by direct interactions with regulatory proteins and serves for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
For research use only, not for clinical use.