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ATP-citrate synthase alpha chain protein 1 (ACLA-1), Recombinant Protein
Cat: RP06756
Size: 0.02 mg (E-Coli)/ 0.02 mg (Yeast)/ 0.1 mg (E-Coli)/ 0.1 mg (Yeast)/ 0.02 mg (Baculovirus)/ 0.02 mg (Mammalian-Cell)/ 0.1 mg (Baculovirus)/ 1 mg (E-Coli)/ 0.1 mg (Mammalian-Cell)/ 1 mg (Yeast)/ 1 mg (Baculovirus)/ 0.5 mg (Mammalian-Cell)
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:
Product Info
Full Product Name
Recombinant Arabidopsis thaliana ATP-citrate synthase alpha chain protein 1 (ACLA-1)
Product Gene Name
ACLA-1 recombinant protein
Product Synonym Gene Name
ACLA-1
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Sequence
MARKKIREYD SKRLVKEHFK RLSGKELPIR SVQINETTDL NELVEKEPWL SSEKLVVKPD MLFGKRGKSG LVALKLDFAD VATFVKERLG KEVEMSGCKG PITTFIVEPF VPHNEEYYLN VVSDRLGCSI SFSECGGIEI EENWDKVKTI FLPTGASLTP EICAPLVATL PLEIKAEIEE FIKVIFTLFQ DLDFTFLEMN PFTLVDGSPY PLDMRGELDD TAAFKNFKKW GDIEFPLPFG RVMSPTESFI HGLDEKTSAS LKFTVLNPKG RIWTMVAGGG ASVIYADTVG DLGYASELGN YAEYSGAPKE DEVLQYARVV IDCATANPDG KSRALVIGGG IANFTDVAAT FNGIIRALKE KEAKLKAARM HIFVRRGGPN YQKGLAKMRA LGDDIGVPIE VYGPEATMTG ICKEAIQYIT AAA
Sequence Positions
1-423, Full length protein
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
46,679 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
ATP-citrate synthase alpha chain protein
NCBI/Uniprot Data
NCBI Accession #
NP_001184954.1
NCBI GI #
334182437
NCBI GenBank Nucleotide #
NM_001198025.1
NCBI GeneID
837610
NCBI Official Full Name
ATP-citrate lyase A-1
NCBI Official Symbol
ACLA-1
NCBI Official Synonym Symbols
ATP-citrate lyase A-1; F20B24.11; F20B24_11
NCBI Protein Information
ATP-citrate lyase A-1
NCBI Summary
One of the three genes encoding subunit A of the trimeric protein ATP Citrate Lyase. Antisense ACLA-1 plants cause a reduction in cytosolic acetyl-CoA metabolism and have upregulation of stress-related genes and down-regulation of primary metabolism and growth genes, suggesting the mutation restricts normal growth and developmental processes and puts the plant into a state of stress.
UniProt Gene Name
ACLA-1
UniProt Synonym Gene Names
ATP-citrate synthase A-1
UniProt Protein Name
ATP-citrate synthase alpha chain protein 1
UniProt Synonym Protein Names
ATP-citrate lyase A-1; Citrate cleavage enzyme A-1
UniProt Primary Accession #
Q9SGY2
UniProt Secondary Accession #
Q56WG2; Q8LAY1
UniProt Related Accession #
Q9SGY2
UniProt Comments
ATP citrate-lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA, used for the elongation of fatty acids and biosynthesis of isoprenoids, flavonoids and malonated derivatives. May supply substrate to the cytosolic acetyl-CoA carboxylase, which generates the malonyl-CoA used for the synthesis of a multitude of compounds, including very long chain fatty acids and flavonoids. Required for normal growth and development and elongation of C18 fatty acids to C20 to C24 fatty acids in seeds. In contrast to all known animal ACL enzymes having a homomeric structure, plant ACLs are composed of alpha and beta chains.
For research use only, not for clinical use.