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ATG4A, Recombinant Protein
Cat: RP06547
Size: 0.05 mg/ 0.1 mg/ 5x0.1 mg
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:
Product Info
Full Product Name
Recombinant Mouse-ear cress ATG4A protein, N-His Tag
Product Synonym Names
ATG4A Autophagy-related protein 4 homolog a Protein autophagy 4a APG4A AtAPG4a Cysteine protease ATG4a
Product Gene Name
ATG4A recombinant protein
Purity
>90% as determined by SDS-PAGE
Format
Lyophilized. Lyophilized from PBS pH 7.4, 0.2% NLS, 5% Trehalose, 5% Mannose, 1mM EDTA.
Host
E Coli
Molecular Weight
46,875 Da
Storage
Store at 2 to 8℃ for one week. Store at -20 to -80℃ for twelve months from the date of receipt. Use a manual defrost freezer and avoid repeated freeze thaw cycles.In general, proteins are provided as lyophilized powder or frozen liquid. They are shipped out with dry ice or blue ice unless customers require otherwise.
Protein Family
Cysteine protease
NCBI/Uniprot Data
NCBI Accession #
NP_001318423.1
NCBI GI #
1063703263
NCBI GenBank Nucleotide #
NM_001337075.1
NCBI GeneID
819020
NCBI Official Full Name
Peptidase family C54 protein
NCBI Official Symbol
AT2G44140
NCBI Official Synonym Symbols
F6E13.27
NCBI Protein Information
Peptidase family C54 protein
UniProt Gene Name
ATG4A
UniProt Synonym Gene Names
APG4A; AtAPG4a; Protein autophagy 4a
UniProt Protein Name
Cysteine protease ATG4a
UniProt Synonym Protein Names
Autophagy-related protein 4 homolog a; AtAPG4a; Protein autophagy 4a
UniProt Primary Accession #
Q8S929
UniProt Secondary Accession #
O80583; Q3EBG5
UniProt Related Accession #
Q8S929
UniProt Comments
Cysteine protease required for autophagy, which is able to cleave the C-terminal part of ATG8 that may be subsequently converted to a smaller form, with a revealed C-terminal glycine. ATG8 is then activated by ATG7 and is subsequently attached to ATG3, another E2-like enzyme, after which the C-terminal glycine of ATG8 is conjugated to phosphatidylethanolamine by an amide bond. This conjugated form has the capacity for the binding to autophagosomes.
For research use only, not for clinical use.