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ARMADILLO BTB ARABIDOPSIS PROTEIN 1 (ABAP1), Recombinant Protein
Cat: RP04422
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:
Product Info
Full Product Name
Recombinant Arabidopsis thaliana ARMADILLO BTB ARABIDOPSIS PROTEIN 1 (ABAP1) , partial
Product Gene Name
ABAP1 recombinant protein
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
81,361 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
ARMADILLO BTB ARABIDOPSIS protein
NCBI/Uniprot Data
NCBI Accession #
NP_196810.5
NCBI GI #
240256284
NCBI GenBank Nucleotide #
NM_121309.6
NCBI GeneID
831145
NCBI Official Full Name
ARMADILLO BTB protein 1
NCBI Official Symbol
ABAP1
NCBI Official Synonym Symbols
ARMADILLO BTB protein 1; T19L5.20; T19L5_20
NCBI Protein Information
ARMADILLO BTB protein 1
NCBI Summary
Encodes a novel Armadillo BTB protein that intreacts with the pre-replication complex and several transcription factors. Overexpression results in decreased cell proliferation and loss of function results in increased cell proliferation suggesting a role in negative regulation of cellular proliferation.
UniProt Gene Name
ABAP1
UniProt Synonym Gene Names
ABAP1
UniProt Protein Name
ARMADILLO BTB ARABIDOPSIS PROTEIN 1
UniProt Primary Accession #
B7U179
UniProt Secondary Accession #
Q8RY88; Q9FYA4
UniProt Related Accession #
B7U179
UniProt Comments
May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins . In association with TCP24, exerts a negative role in cell proliferation in leaves, possibly by inhibiting mitotic DNA replication.
For research use only, not for clinical use.