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Arginine decarboxylase 1 (SPE1), Recombinant Protein
Cat: RP02454
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:
Product Info
Full Product Name
Recombinant Arabidopsis thaliana Arginine decarboxylase 1 (SPE1) , partial
Product Gene Name
SPE1 recombinant protein
Product Synonym Gene Name
SPE1
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
76,175 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
Arginine decarboxylase
NCBI/Uniprot Data
NCBI Accession #
NP_179243.1
NCBI GI #
15227223
NCBI GenBank Nucleotide #
NM_127204.3
NCBI GeneID
816149
NCBI Official Full Name
arginine decarboxylase 1
NCBI Official Symbol
ADC1
NCBI Official Synonym Symbols
ARGDC; ARGDC1; ARGININE DECARBOXYLASE; arginine decarboxylase 1; F1P15.12; F1P15_12; SPE1
NCBI Protein Information
arginine decarboxylase 1
NCBI Summary
encodes a arginine decarboxylase (ADC), a rate-limiting enzyme that catalyzes the first step of polyamine (PA) biosynthesis via ADC pathway in Arabidopsis thaliana. Arabidopsis genome has two ADC paralogs, ADC1 and ADC2. Double mutant analysis showed that ADC genes are essential for the production of PA, and are required for normal seed development. Promoter region of ADC1 contains 742-bp AT-rich transposable element, called AtATE, that belongs to the MITE families of repetitive elements.
UniProt Gene Name
ADC1
UniProt Synonym Gene Names
ADC 1Curated; ADC-OCurated; ARGDC 1Curated; AtADC1
UniProt Protein Name
Arginine decarboxylase 1
UniProt Primary Accession #
Q9SI64
UniProt Secondary Accession #
Q38938
UniProt Related Accession #
Q9SI64
UniProt Comments
Required for the biosynthesis of putrescine. Catalyzes the first step of polyamine (PA) biosynthesis to produce putrescine from arginine (PubMed:11576438, PubMed:15733873, PubMed:25409942). Is a minor contributor to basal arginine decarboxylase (ADC) activity and putrescine biosynthesis (PubMed:25409942). Accumulation of putrescine plays a positive role in freezing tolerance (PubMed:18701673). Production of polyamines is essential for normal seed development (PubMed:15733873). Controls PA homeostasis which is crucial for normal plant growth and development (PubMed:27014322).
For research use only, not for clinical use.