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Arabidopsis thaliana (AUR1), Recombinant Protein
Cat: RP03341
Size: 0.02 mg/ 0.1 mg/ 1 mg/ 5x1 mg
Species: Arabidopsis halleri
Datasheet:
Product Info
Full Product Name
Recombinant Arabidopsis thaliana Arabidopsis thaliana (AUR1)
Product Synonym Names
Aurora-like kinase 1
Product Gene Name
AUR1 recombinant protein
Purity
Greater than 85.7% as determined by SDS-PAGE.
Sequence Positions
Full Length, 1-294aa
Format
Tris-based buffer, 50% glycerol
Host
E Coli
Molecular Weight
52.63 kDa
Storage
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.
Protein Family
Serine/threonine-protein kinase
NCBI/Uniprot Data
NCBI Accession #
NP_195009.1
NCBI GI #
15233958
NCBI GenBank Nucleotide #
NM_119436.3
NCBI GeneID
829419
NCBI Official Full Name
ataurora1
NCBI Official Symbol
AUR1
NCBI Official Synonym Symbols
AtAUR1; ataurora1; T16I18.40; T16I18_40
NCBI Protein Information
ataurora1
NCBI Summary
Encodes a member of a family of Ser/Thr kinases whose activities peak during cell division. Transcripts are abundant in tissues rich in dividing cells like roots and flowers but are low or absent in fully expanded leaves and stems. In interphase cells, the protein is predominantly nuclear. During mitosis, the protein associates with plant-specific cytoskeletal structures (preprophase band, phragmoplast, nascent cell plate) that are necessary for cytokinesis as well as with the microtubule spindle. It specifically phosphorylates Ser10 of histone H3 and colocalizes with phosphorylated histone H3 during mitosis.
UniProt Gene Name
AUR1
UniProt Synonym Gene Names
AtAur1
UniProt Protein Name
Serine/threonine-protein kinase Aurora-1
UniProt Synonym Protein Names
Aurora-like kinase 1
UniProt Primary Accession #
Q9M077
UniProt Secondary Accession #
Q8LBX4
UniProt Related Accession #
Q9M077
UniProt Comments
Phosphorylates specifically 'Ser-10' of histone H3 in vitro and colocalizes with phosphorylated histone H3 during mitosis. Associates with cytoskeletal structures that are necessary for cytokinesis and with the microtubule spindle. Colocalizes also with gamma-tubulin and function in microtubule organizing centers (MTOCs). In contrast with the mammalian B-type Aurora, AUR1 has no kinase activity toward 'Ser-28' of histone H3.
For research use only, not for clinical use.