NCBI Accession #
NP_567022.1
NCBI GenBank Nucleotide #
NM_115406.5
NCBI Official Full Name
protein affected trafficking 2
NCBI Official Symbol
PAT2
NCBI Official Synonym Symbols
AP-3 beta; beta-subunit of adaptor protein complex 3; protein affected trafficking 2; WAT1; WEAK ACID TOLERANT 1
NCBI Protein Information
protein affected trafficking 2
NCBI Summary
Encodes PAT2, a putative beta-subunit of adaptor protein complex 3 (AP-3) that can partially complement the corresponding yeast mutant. Mediates the biogenesis and function of lytic vacuoles.
UniProt Synonym Gene Names
PAT2
UniProt Protein Name
AP3-complex subunit beta-A
UniProt Synonym Protein Names
Adaptor protein complex AP-3 subunit beta-A; Adaptor-related protein complex 3 subunit beta-A; Beta-3B-adaptin; Clathrin assembly protein complex 3 beta-A large chain; Protein-affected trafficking 2
UniProt Primary Accession #
Q9M2T1
UniProt Secondary Accession #
Q93YS9
UniProt Related Accession #
Q9M2T1
UniProt Comments
Part of the AP-3 complex, an adaptor-related complex which seems to be clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to the vacuole. It also function in maintaining the identity of lytic vacuoles and in regulating the transition between storage and lytic vacuoles.