NCBI Accession #
NP_175530.2
NCBI GenBank Nucleotide #
NM_103997.4
NCBI Official Full Name
Integrase-type DNA-binding superfamily protein
NCBI Official Symbol
PLT2
NCBI Official Synonym Symbols
F11M15.6; F11M15_6; PLETHORA 2
NCBI Protein Information
Integrase-type DNA-binding superfamily protein
NCBI Summary
Encodes a member of the AINTEGUMENTA-like (AIL) subclass of the AP2/EREBP family of transcription factors and is essential for quiescent center (QC) specification and stem cell activity. It is a key effector for establishment of the stem cell niche during embryonic pattern formation. It is transcribed in response to auxin accumulation and is dependent on auxin response transcription factors.
UniProt Synonym Gene Names
AIL4
UniProt Protein Name
AP2-like ethylene-responsive transcription factor PLT2
UniProt Synonym Protein Names
Protein AINTEGUMENTA-LIKE 4; Protein PLETHORA 2
UniProt Primary Accession #
Q5YGP7
UniProt Secondary Accession #
Q6PQQ7; Q9SYC2
UniProt Related Accession #
Q5YGP7
UniProt Comments
Probably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways . Master regulator of basal/root fate. Essential for root quiescent center (QC) and columella specification, stem cell activity, as well as for establishment of the stem cell niche during embryogenesis. Modulates the root polar auxin transport by regulating the distribution of PIN genes. Essential role in respecifying pattern and polarity in damaged roots. Direct target of the transcriptional corepressor TPL. Expression levels and patterns regulated post-transcriptionally by root meristem growth factors (RGFs).