NCBI Accession #
O50016.1
NCBI Official Full Name
AP-2 complex subunit sigma
NCBI Official Symbol
ap17
NCBI Official Synonym Symbols
AP-17
NCBI Protein Information
AP-2 complex subunit sigma
UniProt Protein Name
AP-2 complex subunit sigma
UniProt Synonym Protein Names
Clathrin assembly protein 2 sigma small chain; Clathrin coat assembly protein AP17; Clathrin coat-associated protein AP17; Plasma membrane adaptor AP-2 17 kDa protein; Sigma2-adaptin
UniProt Primary Accession #
O50016
UniProt Related Accession #
O50016
UniProt Comments
Component of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. AP2S1/AP17 is a subunit of the plasma membrane adaptor. The complex binds polyphosphoinositides.