NCBI Accession #
NP_196192.1
NCBI GenBank Nucleotide #
NM_120655.4
NCBI Official Full Name
anthranilate synthase alpha subunit 1
NCBI Official Symbol
ASA1
NCBI Official Synonym Symbols
A-METHYL TRYPTOPHAN RESISTANT 1; AMT1; ANTHRANILATE SYNTHASE ALPHA SUBUNIT; anthranilate synthase alpha subunit 1; JASMONATE-INDUCED DEFECTIVE LATERAL ROOT 1; JDL1; MJJ3.14; MJJ3_14; TRP5; TRYPTOPHAN BIOSYNTHESIS 5; WEAK ETHYLENE INSENSITIVE 2; WEI2
NCBI Protein Information
anthranilate synthase alpha subunit 1
NCBI Summary
ASA1 encodes the alpha subunit of anthranilate synthase, which catalyzes the rate-limiting step of tryptophan synthesis. ASA1 is induced by ethylene, and forms a link between ethylene signalling and auxin synthesis in roots.
UniProt Synonym Gene Names
AMT1; JDL1; TRP5; WEI2
UniProt Protein Name
Anthranilate synthase alpha subunit 1, chloroplastic
UniProt Synonym Protein Names
Anthranilate synthase component 1-1; Anthranilate synthase component I-1; Protein A-METHYL TRYPTOPHAN RESISTANT 1; Protein JASMONATE-INDUCED DEFECTIVE LATERAL ROOT 1; Protein TRYPTOPHAN BIOSYNTHESIS 5; Protein WEAK ETHYLENE INSENSITIVE 2
UniProt Primary Accession #
P32068
UniProt Related Accession #
P32068
UniProt Comments
Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS to produce anthranilate. Plays an important regulatory role in auxin production via the tryptophan-dependent biosynthetic pathway.