Ankyrin repeat domain-containing protein 2 (AKR2), Recombinant Protein
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Ankyrin repeat domain-containing protein 2 (AKR2), Recombinant Protein

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Cat: RP01578
Size: 0.02 mg (E-Coli)/ 0.02 mg (Yeast)/ 0.1 mg (E-Coli)/ 0.1 mg (Yeast)/ 0.02 mg (Baculovirus)/ 0.02 mg (Mammalian-Cell)/ 0.1 mg (Baculovirus)/ 1 mg (E-Coli)/ 1 mg (Yeast)/ 0.1 mg (Mammalian-Cell)/ 1 mg (Baculovirus)/ 0.5 mg (Mammalian-Cell)
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:

Product Info

Full Product Name
Recombinant Arabidopsis thaliana Ankyrin repeat domain-containing protein 2 (AKR2)
Product Gene Name
AKR2 recombinant protein
Product Synonym Gene Name
AKR2
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Sequence
MASNSEKNPL LSDEKPKSTE ENKSSKPESA SGSSTSSAMP GLNFNAFDFS NMASILNDPS IREMAEQIAK DPAFNQLAEQ LQRSIPNAGQ EGGFPNFDPQ QYVNTMQQVM HNPEFKTMAE KLGTALVQDP QMSPFLDAFS NPETAEHFTE RMARMKEDPE LKPILDEIDA GGPSAMMKYW NDPEVLKKLG EAMGMPVAGL PDQTVSAEPE VAEEGEEEES IVHQTASLGD VEGLKAALAS GGNKDEEDSE GRTALHFACG YGELKCAQVL IDAGASVNAV DKNKNTPLHY AAGYGRKECV SLLLENGAAV TLQNLDEKTP IDVAKLNSQL EVVKLLEKDA FL
Sequence Positions
1-342, Full length protein
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
36,984 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
Probable palmitoyltransferase

NCBI/Uniprot Data

NCBI Accession #
NP_195270.1
NCBI GI #
15237008
NCBI GenBank Nucleotide #
NM_119710.5
NCBI GeneID
829697
NCBI Official Full Name
ankyrin repeat-containing protein 2
NCBI Official Symbol
AKR2
NCBI Official Synonym Symbols
AFT; AKR2A; ankyrin repeat-containing protein 2; F15J1.20; F15J1_20
NCBI Protein Information
ankyrin repeat-containing protein 2
NCBI Summary
Involved in targeting of chloroplast outer membrane proteins to the chloroplast. Double mutants of AKR2A and the highly homologous AKR2B have yellow leaves, significantly reduced chloroplast proteins, and no thylakoid membranes.
UniProt Gene Name
AKR2A
UniProt Synonym Gene Names
AtAKR2
UniProt Protein Name
Ankyrin repeat domain-containing protein 2A
UniProt Primary Accession #
Q9SAR5
UniProt Secondary Accession #
O81128; Q9SVX0
UniProt Related Accession #
Q9SAR5
UniProt Comments
Exhibits chaperone activity toward chloroplast outer envelope membrane, mitochondrion outer membrane, endoplasmic reticulum membrane and peroxisomal proteins, by recruiting specific proteins containing a single transmembrane associated with an AKR2A-binding sequence (ABS) and subsequently binding glycolipids (e.g. monogalactosyldiacylglycerol (MGDG) and phosphatidylglycerol (PG)) present in the membrane of the target organelle (PubMed:18193034, PubMed:20215589, PubMed:25203210). Seems to be involved in the regulation of hydrogen peroxide levels during biotic and abiotic stresses by optimizing the ascorbate peroxidase 3 (APX3) hydrogen peroxide-degrading activity. This regulation might be monitored by GRF6. Cytosolic targeting factor for chloroplast outer membrane (COM) proteins that mediates sorting and targeting of nascent chloroplast outer envelope membrane (OEM) proteins to the chloroplast. Facilitates the targeting of OEP7 to chloroplasts (PubMed:18193034). Facilitates the targeting of APX3 to peroxisomes. Involved in cellular metabolism (e.g. peroxisome activity) and required for plant growth and development (PubMed:20215589).

For research use only, not for clinical use.