NCBI Accession #
NP_190398.1
NCBI GenBank Nucleotide #
NM_114684.5
NCBI Official Full Name
anaphase-promoting complex subunit 8
NCBI Official Symbol
APC8
NCBI Official Synonym Symbols
anaphase-promoting complex subunit 8; CDC23
NCBI Protein Information
anaphase-promoting complex subunit 8
NCBI Summary
anaphase-promoting complex or cyclosome subunit
UniProt Synonym Gene Names
CDC23; CDC23 homolog
UniProt Protein Name
Anaphase-promoting complex subunit 8
UniProt Synonym Protein Names
Cell division cycle protein 23 homolog; CDC23 homolog; Cyclosome subunit 8
UniProt Primary Accession #
Q9STS3
UniProt Secondary Accession #
Q570L3; Q93ZW8
UniProt Related Accession #
Q9STS3
UniProt Comments
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex controls several key steps in the cell cycle by mediating ubiquitination and subsequent degradation of target proteins such as cyclins. The APC/C complex is required for the female gametophyte development and is involved in several aspect of development by controlling cell division and cell elongation. Involved in the control of endoreduplication.