NCBI Accession #
NP_178543.2
NCBI GenBank Nucleotide #
NM_126495.3
NCBI Official Full Name
anaphase-promoting complex/cyclosome 2
NCBI Official Symbol
APC2
NCBI Official Synonym Symbols
anaphase-promoting complex/cyclosome 2; F28I8.30; F28I8_30
NCBI Protein Information
anaphase-promoting complex/cyclosome 2
NCBI Summary
a highly conserved ubiquitin-protein ligase involved in cell cycle regulation
UniProt Protein Name
Anaphase-promoting complex subunit 2
UniProt Synonym Protein Names
Cyclosome subunit 2
UniProt Primary Accession #
Q8H1U5
UniProt Secondary Accession #
Q8GX39; Q9SJ93
UniProt Related Accession #
Q8H1U5
UniProt Comments
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex controls several key steps in the cell cycle by mediating ubiquitination and subsequent degradation of target proteins such as cyclins. The APC/C complex is required for the female gametophyte development and is involved in several aspect of development by controlling cell division and cell elongation. Involved in the control of endoreduplication.