NCBI Accession #
NP_001189819.1
NCBI GenBank Nucleotide #
NM_001202890.2
NCBI Official Full Name
anaphase-promoting complex/cyclosome 11
NCBI Official Symbol
APC11
NCBI Official Synonym Symbols
anaphase-promoting complex/cyclosome 11; F10A16.17; F10A16_17
NCBI Protein Information
anaphase-promoting complex/cyclosome 11
NCBI Summary
Subunit of the anaphase promoting complex, a ubiquitin ligase complex that regulates progression through the cell cycle.
UniProt Protein Name
Anaphase-promoting complex subunit 11
UniProt Synonym Protein Names
Cyclosome subunit 11
UniProt Primary Accession #
Q9M9L0
UniProt Secondary Accession #
Q940X6; F4J9K5
UniProt Comments
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex controls several key steps in the cell cycle by mediating ubiquitination and subsequent degradation of target proteins such as cyclins. The APC/C complex is required for the female gametophyte development and is involved in several aspect of development by controlling cell division and cell elongation. Involved in the control of endoreduplication. May recruit the E2 ubiquitin-conjugating enzymes to the complex .