NCBI Accession #
NP_188876.1
NCBI GenBank Nucleotide #
NM_113135.3
NCBI Official Full Name
alternative oxidase 1A
NCBI Official Symbol
AOX1A
NCBI Official Synonym Symbols
alternative oxidase 1A; AOX1A; ATAOX1A
NCBI Protein Information
alternative oxidase 1A
NCBI Summary
Encodes AOX1a, an isoform of alternative oxidase that is expressed in rosettes, flowers, and root. The alternative oxidase of plant mitochondria transfers electrons from the ubiquinone pool to oxygen without energy conservations. It is regulated through transcriptional control and by pyruvate. Plays a role in shoot acclimation to low temperature. Also is capable of ameliorating reactive oxygen species production when the cytochrome pathway is inhibited. AOX1a also functions as a marker for mitochondrial retrograde response.
UniProt Synonym Gene Names
AOX1; HSR3
UniProt Protein Name
Ubiquinol oxidase 1a, mitochondrial
UniProt Synonym Protein Names
Alternative oxidase 1a
UniProt Entry Name
AOX1A_ARATH
UniProt Primary Accession #
Q39219
UniProt Secondary Accession #
O23914; P93734; Q9ZRT8
UniProt Related Accession #
Q39219
UniProt Comments
Catalyzes the cyanide-resistant oxidation of ubiquinol and the reduction of molecular oxygen to water, but does not translocate protons and consequently is not linked to oxidative phosphorylation. Increases respiration when the cytochrome respiratory pathway is restricted, or in response to low temperatures.