Aldo-keto reductase family 4 member C9 (AKR4C9), Recombinant Protein
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Aldo-keto reductase family 4 member C9 (AKR4C9), Recombinant Protein

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Cat: RP06788
Size: 0.02 mg (E-Coli)/ 0.02 mg (Yeast)/ 0.1 mg (E-Coli)/ 0.1 mg (Yeast)/ 0.02 mg (Baculovirus)/ 0.02 mg (Mammalian-Cell)/ 0.1 mg (Baculovirus)/ 1 mg (E-Coli)/ 1 mg (Yeast)/ 0.1 mg (Mammalian-Cell)/ 1 mg (Baculovirus)/ 0.5 mg (Mammalian-Cell)
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:

Product Info

Full Product Name
Recombinant Arabidopsis thaliana Aldo-keto reductase family 4 member C9 (AKR4C9)
Product Gene Name
AKR4C9 recombinant protein
Product Synonym Gene Name
AKR4C9
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Sequence
MANAITFFKL NTGAKFPSVG LGTWQASPGL VGDAVAAAVK IGYRHIDCAQ IYGNEKEIGA VLKKLFEDRV VKREDLFITS KLWCTDHDPQ DVPEALNRTL KDLQLEYVDL YLIHWPARIK KGSVGIKPEN LLPVDIPSTW KAMEALYDSG KARAIGVSNF STKKLADLLE LARVPPAVNQ VECHPSWRQT KLQEFCKSKG VHLSAYSPLG SPGTTWLKSD VLKNPILNMV AEKLGKSPAQ VALRWGLQMG HSVLPKSTNE GRIKENFNVF DWSIPDYMFA KFAEIEQARL VTGSFLVHET LSPYKSIEEL WDGEI
Sequence Positions
1-315, Full length protein
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
31,680 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
Aldo-keto reductase family

NCBI/Uniprot Data

NCBI Accession #
NP_001031505.1
NCBI GI #
79324628
NCBI GenBank Nucleotide #
NM_001036428.3
NCBI GeneID
818354
NCBI Official Full Name
NAD(P)-linked oxidoreductase superfamily protein
NCBI Official Symbol
ChlAKR
NCBI Official Synonym Symbols
AKR4C9; Aldo-keto reductase family 4 member C9; Chloroplastic aldo-keto reductase; T8P21.32
NCBI Protein Information
NAD(P)-linked oxidoreductase superfamily protein
NCBI Summary
Encodes an NADPH-dependent aldo-keto reductase that can act on a wide variety of substrates in vitro including saturated and unsaturated aldehydes, steroids, and sugars. GFP-tagged AKR4C9 localizes to the chloroplast where it may play a role in detoxifying reactive carbonyl compounds that threaten to impair the photosynthetic process. Transcript levels for this gene are up-regulated in response to cold, salt, and drought stress.
UniProt Gene Name
AKR4C9
UniProt Synonym Gene Names
AtChlAKR
UniProt Protein Name
NADPH-dependent aldo-keto reductase, chloroplastic
UniProt Synonym Protein Names
Aldo-keto reductase family 4 member C9
UniProt Primary Accession #
Q0PGJ6
UniProt Secondary Accession #
O80945; Q2V420; Q84W94
UniProt Related Accession #
Q0PGJ6
UniProt Comments
Oxidoreductase acting on a broad range of substrates: reduces ketosteroids, aromatic aldehydes, ketones, sugars and other aliphatic aldehydes, and oxidizes hydroxysteroids (PubMed:19616008). Aldehyde reductase that catalyzes the reduction of the aldehyde carbonyl groups on saturated and alpha,beta-unsaturated aldehydes (PubMed:21169366). No activity on alpha,beta-unsaturated ketones (PubMed:21169366). Can use propionaldehyde, butyraldehyde, methylglyoxal, (E)-2-pentenal, (E)-2-hexenal, (Z)-3-hexenal and (E)-2-nonenal as substrates, propenal (acrolein), crotonaldehyde, but not 2-butanone, 3-buten-2-one or 1-penten-3-one (PubMed:21169366). May function as detoxifiying enzyme by reducing a range of toxic aldehydes and ketones produced during stress (PubMed:19616008).

For research use only, not for clinical use.