NCBI Accession #
NP_001078019.1
NCBI GenBank Nucleotide #
NM_001084550.1
NCBI Official Full Name
NAD(P)-linked oxidoreductase superfamily protein
NCBI Official Symbol
AKR4C8
NCBI Official Synonym Symbols
Aldo-keto reductase family 4 member C8; T8P21.6
NCBI Protein Information
NAD(P)-linked oxidoreductase superfamily protein
NCBI Summary
Encodes an NADPH-dependent aldo-keto reductase that can act on a wide variety of substrates in vitro including aliphatic and aromatic aldehydes and steroids. Transcript levels for this gene are up-regulated in response to cold, salt, and drought stress.
UniProt Protein Name
Aldo-keto reductase family 4 member C8
UniProt Primary Accession #
O80944
UniProt Secondary Accession #
Q3E6N6; Q3EBK9; Q93YR4; B3H474
UniProt Related Accession #
O80944
UniProt Comments
Oxidoreductase acting on a broad range of substrates: reduces ketosteroids, aromatic aldehydes, ketones, sugars and other aliphatic aldehydes, and oxidizes hydroxysteroids. May function as detoxifiying enzyme by reducing a range of toxic aldehydes and ketones produced during stress.