NCBI Accession #
NP_173858.5
NCBI GenBank Nucleotide #
NM_102294.7
NCBI Official Full Name
OxaA/YidC-like membrane insertion protein
NCBI Official Symbol
ALB4
NCBI Official Synonym Symbols
ALBINA 4; ARABIDOPSIS THALIANA ENVELOPE MEMBRANE INTEGRASE; ARTEMIS; F21J9.16
NCBI Protein Information
OxaA/YidC-like membrane insertion protein
NCBI Summary
Homologue of the Alb3/Oxa1/YidC family. ALB4 is almost identical to the Alb3/Oxa1/YidC domain of the previously described 110 kDa inner envelope protein ARTEMIS. However, ALB4 is expressed as a separate 55 kDa protein and is located in the thylakoid membrane of chloroplasts. Analysis of a T-DNA insertion line with a reduced level of Alb4 revealed chloroplasts with an altered ultrastructure. Mutant plastids are larger, more spherical in appearance and the grana stacks within the mutant lines are less appressed than in the wild-type chloroplasts. ALB4 is required for proper chloroplast biogenesis.
UniProt Synonym Gene Names
Ath4Curated
UniProt Protein Name
ALBINO3-like protein 1, chloroplastic
UniProt Synonym Protein Names
Arabidopsis thaliana envelope membrane integrase
UniProt Primary Accession #
Q9FYL3
UniProt Secondary Accession #
Q1RPP7; Q9FYL4
UniProt Related Accession #
Q9FYL3
UniProt Comments
Required for the insertion of some light harvesting chlorophyll-binding proteins (LHCP) into the chloroplast thylakoid membrane. Plays a role in the accumulation of some cytochrome b6f components in the thylakoid membrane (PubMed:26265777). Required for the assembly and/or stability of the F1F0 ATP synthase in chloroplast thylakoid membranes. Functions to stabilize or promote assembly of F1 during its attachment to the membrane-embedded F0 part (PubMed:19995738). Participates with STIC2 in thylakoid protein targeting. May function with a specific subset of thylakoidal proteins (PubMed:28684427).