NCBI Accession #
NP_199347.2
NCBI GenBank Nucleotide #
NM_123902.3
NCBI Official Full Name
cytochrome P450, family 707, subfamily A, polypeptide 3
NCBI Official Symbol
CYP707A3
NCBI Official Synonym Symbols
''cytochrome P450; cytochrome P450; family 707; K9E15.12; K9E15_12; polypeptide 3; polypeptide 3''; subfamily A
NCBI Protein Information
cytochrome P450, family 707, subfamily A, polypeptide 3
NCBI Summary
Encodes a protein with ABA 8'-hydroxylase activity; involved in ABA catabolism. Mutant analyses show that disruption in the gene results in more drought tolerance whereas overexpression results in increased transpiration rate and reduced drought tolerance. Gene involved in postgermination growth. Plant P450 CYP707A3, ABA 8'-hydroxylase, binds enantioselectively (+)-ABA but not (-)-ABA, whereas the enzyme binds both enantiomers of AHI1 (a structural ABA analogue used as ABA 8'-hydroxylase competitive inhibitor).
UniProt Gene Name
CYP707A3
UniProt Synonym Gene Names
ABA 8'-hydroxylase 3
UniProt Protein Name
Abscisic acid 8'-hydroxylase 3
UniProt Synonym Protein Names
Cytochrome P450 707A3
UniProt Primary Accession #
Q9FH76
UniProt Secondary Accession #
Q3E8G7
UniProt Related Accession #
Q9FH76
UniProt Comments
Involved in the oxidative degradation of abscisic acid, but not in the isomerization of the produced 8'-hydroxyabscisic acid (8'-OH-ABA) to (-)-phaseic acid (PA). Involved in the control of postgermination growth.