NCBI Accession #
NP_176196.1
NCBI GenBank Nucleotide #
NM_104680.3
NCBI Official Full Name
ABC-2 and Plant PDR ABC-type transporter family protein
NCBI Official Symbol
PEN3
NCBI Official Synonym Symbols
ABCG36; ARABIDOPSIS PLEIOTROPIC DRUG RESISTANCE 8; Arabidopsis thaliana ATP-binding cassette G36; ARABIDOPSIS THALIANA ATP-BINDING CASSETTE G36; ATABCG36; ATP-binding cassette G36; ATP-BINDING CASSETTE G36; ATPDR8; F23H11.19; F23H11_19; PDR8; PENETRATION
NCBI Protein Information
ABC-2 and Plant PDR ABC-type transporter family protein
NCBI Summary
ATP binding cassette transporter. Localized to the plasma membrane in uninfected cells. In infected leaves, the protein concentrated at infection sites. Contributes to nonhost resistance to inappropriate pathogens that enter by direct penetration in a salicylic acid#Aeidependent manner. Required for mlo resistance. Has Cd transporter activity (Cd2+ extrusion pump) and contributes to heavy metal resistance.
UniProt Synonym Gene Names
PDR8; PEN3; ABC transporter ABCG.36; AtABCG36
UniProt Protein Name
ABC transporter G family member 36
UniProt Synonym Protein Names
Pleiotropic drug resistance protein 8; Protein PENETRATION 3
UniProt Primary Accession #
Q9XIE2
UniProt Secondary Accession #
Q8VXW5
UniProt Related Accession #
Q9XIE2
UniProt Comments
Key factor that controls the extent of cell death in the defense response. Necessary for both callose deposition and glucosinolate activation in response to pathogens. Required for limiting invasion by nonadapted powdery mildews. Confers resistance to cadmium (Cd) and lead (Pb), probably as an efflux pump of Cd2+ or Cd conjugates, and possibly, of chemicals that mediate pathogen resistance.